2021
Authors
Perez Herrera, RA; Bravo, M; Leandro, D; Novais, S; Pradas, J; Lopez Amo, M;
Publication
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
Abstract
In this work, a multi-parameter point sensor based on the combination of Fabry-Perot (FP) and the anti-resonant (AR) reflecting guidance in cascade configuration is proposed and experimentally demonstrated. This structure, based on FP interference and AR reflecting guidance, was fabricated with two different air micro-cavities. The attained experimental results showed different strain and temperature sensitivities for the antiresonance contribution. However, when analyzing the FP interference, only strain sensitivity was observed, demonstrating that this air micro-cavity was also insensitive to temperature variations.
2021
Authors
Rosolem, JB; Penze, RS; Floridia, C; Peres, R; Vasconcelos, D; Ramos Junior, MA;
Publication
Sensors
Abstract
2021
Authors
Silva, AdA; Floridia, C; Rosolem, JB;
Publication
Sensors
Abstract
2021
Authors
Rosolem, JB; Penze, RS; Floridia, C; Bassan, FR; Peres, R; Costa, EFd; de Araujo Silva, A; Coral, AD; Junior, JRN; Vasconcelos, D; Junior, MAR;
Publication
IEEE Sensors Journal
Abstract
2021
Authors
Bassan, FR; Rosolem, JB; Floridia, C; Aires, BN; Peres, R; Aprea, JF; Nascimento, CAM; Fruett, F;
Publication
Sensors
Abstract
2020
Authors
Paiva, JS; Jorge, PAS; Ribeiro, RSR; Balmana, M; Campos, D; Mereiter, S; Jin, CS; Karlsson, NG; Sampaio, P; Reis, CA; Cunha, JPS;
Publication
SCIENTIFIC REPORTS
Abstract
With the advent of personalized medicine, there is a movement to develop "smaller" and "smarter" microdevices that are able to distinguish similar cancer subtypes. Tumor cells display major differences when compared to their natural counterparts, due to alterations in fundamental cellular processes such as glycosylation. Glycans are involved in tumor cell biology and they have been considered to be suitable cancer biomarkers. Thus, more selective cancer screening assays can be developed through the detection of specific altered glycans on the surface of circulating cancer cells. Currently, this is only possible through time-consuming assays. In this work, we propose the "intelligent" Lab on Fiber (iLoF) device, that has a high-resolution, and which is a fast and portable method for tumor single-cell type identification and isolation. We apply an Artificial Intelligence approach to the back-scattered signal arising from a trapped cell by a micro-lensed optical fiber. As a proof of concept, we show that iLoF is able to discriminate two human cancer cell models sharing the same genetic background but displaying a different surface glycosylation profile with an accuracy above 90% and a speed rate of 2.3 seconds. We envision the incorporation of the iLoF in an easy-to-operate microchip for cancer identification, which would allow further biological characterization of the captured circulating live cells.
The access to the final selection minute is only available to applicants.
Please check the confirmation e-mail of your application to obtain the access code.