Abstract

Abstract
The use of electronic health records to support health activities is currently quite widespread, due to the increasing complexity of health care and the need to optimize human and material resources. The requirement of health care professionals to access clinical information expeditiously is a key factor in the quality of health care services. Therefore, the assessment of the usability of the health of applications is crucial. The objective of this study was to evaluate the usability of SClinico through a questionnaire especially developed, and it took place in an hospital environment. The SClinico is an electronic health record application used on a large scale in public Portuguese healthcare institutions. The results show that SClinico has some usability issues that need to be improved. Among these we highlight the need to take a holistic view of the patient's health record and simultaneously quick access to relevant details for different clinical situations.

Abstract

Abstract

Abstract
Suicide is a serious public health problem and is among the top ten causes of death worldwide for all age groups. It is the third leading cause among 15-35-year olds. The main objective of this quasi-experimental, quantitative, and cross-sectional study was to compare the levels of suicidal ideation among college students (n = 50) and nonstudents (n = 51). Subjects were compared according to sex, age, place of residence, living arrangements, educational level, and occupational status using the Suicidal Ideation Questionnaire. The sample consisted of 101 individuals aged 18- 25 years, Mean of 21.44 years and Standard Deviation of 2.43. The results showed higher levels of suicidal ideation among the non-college students. Statistically significant effects were found among the following variables: level of education, occupational status, living alone, and presence of anxiety disorder and/or depression. The findings of this study suggest the need for suicide prevention measures in order to reduce deaths by suicide and suicide attempt rate.

Abstract
Background: Catechol-O-methyltransferase (COMT) is a catabolic enzyme involved in the degradation of bioactive molecules including the neurotransmitters epinephrine, norepinephrine, and dopamine. Higher COMT activity in depressive patients in comparison to non-depressed individuals has been reported. The effect of aerobic exercise on depressive patients has been studied and a number of researchers and clinicians believe it to be effective in the treatment of depression and to be involved in several molecular underlying mechanisms. However, the effect of physical exercise on this enzyme activity is unknown, and it remains to be elucidated if chronic exercise changes COMT activity. This randomized control trial evaluates the effects of chronic exercise on peripheral COMT (S-COMT) activity in women with depressive disorder. Methods: Fourteen women (aged: 51.4 + 10.5 years) diagnosed with depression (according to International Classification of Diseases-10) were randomized to one of two groups: pharmacotherapy plus physical exercise (n=7) or only pharmacotherapy (n=7). The aerobic exercise program was supervised, lasting between 45-50 min/session, three times/week for 16 weeks. Erythrocyte soluble COMT were assessed prior to and after the exercise program. Results: Exercise group when compared to a control group presented a significant decrease (p=0.02, r=-0.535) in S-COMT activity between baseline and post-intervention. Limitations: These data are preliminary outcomes from a small sample and should be replicated. Conclusions: Chronic exercise therapy combined with pharmacotherapy leads to significant decrease in S-COMT activity. Our results provide evidence that exercise interferes with S-COMT activity, a molecular mechanism involved in depression. (C) 2016 Published by Elsevier B.V.