2025
Authors
Rocha, CD; Carneiro, I; Torres, M; Oliveira, HP; Pires, EJS; Silva, MF;
Publication
PROGRESS IN BIOMEDICAL ENGINEERING
Abstract
Stroke, a vascular disorder affecting the nervous system, is the third-leading cause of death and disability combined worldwide. One in every four people aged 25 and older will face the consequences of this condition, which typically causes loss of limb function, among other disabilities. The proposed review analyzes the mechanisms of stroke and their influence on the disease outcome, highlighting the critical role of rehabilitation in promoting recovery of the upper limb (UL) and enhancing the quality of life of stroke survivors. Common outcome measures and the specific targeted UL features are described, along with emerging supplementary therapies found in the literature. Stroke survivors often develop compensatory strategies to cope with limitations in UL function, which must be detected and corrected during rehabilitation to facilitate long-term recovery. Recent research on the automated detection of compensatory movements has explored pressure, wearable, marker-based motion capture systems, and vision sensors. Although current approaches have certain limitations, they establish a strong foundation for future innovations in post-stroke UL rehabilitation, promoting a more effective recovery.
2025
Authors
Silva, JA; Silva, MF; Oliveira, HP; Rocha, CD;
Publication
APPLIED SCIENCES-BASEL
Abstract
Stroke often leads to severe motor impairment, especially in the upper limbs, greatly reducing a patient's ability to perform daily tasks. Effective rehabilitation is essential to restore function and improve quality of life. Traditional therapies, while useful, may lack engagement, leading to low motivation and poor adherence. Gamification-using game-like elements in non-game contexts-offers a promising way to make rehabilitation more engaging. The authors explore a gamified rehabilitation system designed in Unity 3D using a Kinect V2 camera. The game includes key features such as adjustable difficulty, real-time and predominantly positive feedback, user friendliness, and data tracking for progress. The evaluations were conducted with 18 healthy participants, most of whom had prior virtual reality experience. About 77% found the application highly motivating. While the gameplay was well received, the visual design was noted as lacking engagement. Importantly, all users agreed that the game offers a broad range of difficulty levels, making it accessible to various users. The results suggest that the system has strong potential to improve rehabilitation outcomes and encourage long-term use through enhanced motivation and interactivity.
2025
Authors
Sousa, P; Sousa, H; Pereira, T; Batista, E; Gouveia, P; Oliveira, HP;
Publication
38th IEEE International Symposium on Computer-Based Medical Systems, CBMS 2025, Madrid, Spain, June 18-20, 2025
Abstract
Advancements in the care for patients with breast cancer have demanded the development of biomechanical breast models for the planning and risk mitigation of such invasive surgical procedures. However, these approaches require large amounts of high-quality magnetic resonance imaging (MRI) training data that is of difficult acquisition and availability. Although this can be solved using synthetic data, generating high resolution images comes at the price of very high computational constraints and tipically low performances. On the other hand, producing lower resolution samples yields better results and efficiency but falls short of meeting health professional standards. Therefore, this work aims to validate a joint approach between lower resolution generative models and the proposed superresolution architecture, titled Shifted Window Image Restoration (SWinIR), which was used to achieve a 4x increase in image size of breast cancer patient MRI samples. Results prove to be promising and to further expand upon the super-resolution state-of-the-art, achieving good maximum peak signal-to-noise ratio of 41.36 and structural similarity index values of 0.962 and thus beating traditional methods and other machine learning architectures. © 2025 IEEE.
2025
Authors
Fernandes, RF; Oliveira, HS; Ribeiro, PP; Oliveira, HP;
Publication
Pattern Recognition and Image Analysis - 12th Iberian Conference, IbPRIA 2025, Coimbra, Portugal, June 30 - July 3, 2025, Proceedings, Part II
Abstract
Medical image captioning is an essential tool to produce descriptive text reports of medical images. One of the central problems of medical image captioning is their poor domain description generation because large pre-trained language models are primarily trained in non-medical text domains with different semantics of medical text. To overcome this limitation, we explore improvements in contrastive learning for X-ray images complemented with soft prompt engineering for medical image captioning and conditional text decoding for caption generation. The main objective is to develop a softprompt model to improve the accuracy and clinical relevance of the automatically generated captions while guaranteeing their complete linguistic accuracy without corrupting the models’ performance. Experiments on the MIMIC-CXR and ROCO datasets showed that the inclusion of tailored soft-prompts improved accuracy and efficiency, while ensuring a more cohesive medical context for captions, aiding medical diagnosis and encouraging more accurate reporting. © 2025 Elsevier B.V., All rights reserved.
2025
Authors
Descalzi, O; Facao, M; Carvalho, MI; Cartes, C; Brand, HR;
Publication
PHYSICA D-NONLINEAR PHENOMENA
Abstract
We study the dynamics as well as the interaction of stable dissipative solitons (DSs) of the cubic complex Ginzburg-Landau equation which are stabilized only by nonlinear gradient (NLG) terms. First we review stationary, periodic, quasi-periodic, and chaotic solutions. Then we investigate sudden transitions to chaotic from periodic and vice versa as a function of one parameter, as well as different outcomes, for fixed parameters, when varying the initial condition. In addition, we present a quasi-analytic approach to evaluate the separation of nearby trajectories for the case of stationary DSs as well as for periodic DSs, both stabilized by nonlinear gradient terms. In a separate section collisions between different types of DSs are reviewed. First we present a concise review of collisions of DSs without NLG terms and then the results of collisions between stationary DSs stabilized by NLG terms are summarized focusing on the influence of the nonlinear gradient term associated with the Raman effect. We point out that both, meandering oscillatory bound states as well as bound states with large amplitude oscillations appear to be specific for coupled cubic complex Ginzburg-Landau equations with a stabilizing cubic nonlinear gradient term.
2025
Authors
Guerra, AR; Oliveira, LR; Rodrigues, GO; Pinheiro, MR; Carvalho, MI; Tuchin, VV; Oliveira, LM;
Publication
JOURNAL OF BIOPHOTONICS
Abstract
Measuring the density of tartrazine (TZ) powder allowed to develop a protocol for fast preparation of aqueous solutions with a desired concentration. The stability time of these solutions decreases exponentially with the increase of TZ concentration: solutions with TZ concentrations below 25% remain stable for more than 24 h, while the solution with 60% TZ remains stable only for 35 min. To validate the developed protocol, muscle samples were immersed in the 40% TZ solution and, as expected, the tissue transparency increased smoothly and exponentially during the whole treatment of 30 min. The diffusion time of TZ in ex vivo skeletal muscle was quantitatively determined with high accuracy as tau TZ = 5.39 +/- 0.49 min for sample thickness of 0.5 mm. By measuring the refractive index of TZ solutions during preparation, it will be easier to prepare such solutions in a fast manner for future research on tissue optical clearing.
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