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Publications

Publications by CTM

2022

Automated Adequacy Assessment of Cervical Cytology Samples Using Deep Learning

Authors
Mosiichuk, V; Viana, P; Oliveira, T; Rosado, L;

Publication
PATTERN RECOGNITION AND IMAGE ANALYSIS (IBPRIA 2022)

Abstract
Cervical cancer has been among the most common causes of cancer death in women. Screening tests such as liquid-based cytology (LBC) were responsible for a substantial decrease in mortality rates. Still, visual examination of cervical cells on microscopic slides is a time-consuming, ambiguous and challenging task, aggravated by inadequate sample quality (e.g. low cellularity or the presence of obscuring factors like blood or inflammation). While most works in the literature are focused on the automated detection of cervical lesions to support diagnosis, to the best of our knowledge, none of them address the automated assessment of sample adequacy, as established by The Bethesda System (TBS) guidelines. This work proposes a new methodology for automated adequacy assessment of cervical cytology samples. Since the most common reason for rejecting samples is the low count of the squamous nucleus, our approach relies on a deep learning object detection model for the detection and counting of different types of nuclei present in LBC samples. A dataset of 41 samples with a total of 42387 nuclei manually annotated by experienced specialists was used, and the best solution proposed achieved promising results for the automated detection of squamous nuclei (AP of 82.4%, Accuracy of 79.8%, Recall of 73.8% and Fl score of 81.5%). Additionally, by merging the developed automated cell counting approach with the adequacy criteria stated by the TBS guidelines, we validated our approach by correctly classifying an entire subset of 12 samples as adequate or inadequate.

2022

Classification of Table Tennis Strokes in Wearable Device using Deep Learning

Authors
Ferreira, NM; Torres, JM; Sobral, P; Moreira, R; Soares, C;

Publication
ICAART: PROCEEDINGS OF THE 14TH INTERNATIONAL CONFERENCE ON AGENTS AND ARTIFICIAL INTELLIGENCE - VOL 3

Abstract
Analysis of sports performance using mobile and wearable devices is becoming increasingly popular, helping users improve their sports practice. In this context, the goal of this work has been the development of an Apple Watch application, capable of detecting important strokes in the table tennis sport, using a deep learning (DL) model. A dataset of table tennis strokes has been created based on the watch's accelerometer and gyroscope sensors. The dataset collection was done in the Portuguese table tennis federation training sites, from several athletes, supervised by their coaches. To obtain the best DL model, three different architecture models where trained, compared and evaluated, using the complete dataset: a LSTM based on Create ML/Core ML frameworks (62.70% F1 score) and two Tensorflow based architectures, a CNN-LSTM (96.02% F1 score) and a ConvLSTM (97.33% F1 score).

2022

Characterization and modeling of resistive switching phenomena in IGZO devices

Authors
Carvalho, G; Pereira, ME; Silva, C; Deuermeier, J; Kiazadeh, A; Tavares, V;

Publication
AIP ADVANCES

Abstract
This study explores the resistive switching phenomena present in 4 mu m(2) amorphous Indium-Gallium-Zinc Oxide (IGZO) memristors. Despite being extensively reported in the literature, not many studies detail the mechanisms that dominate conduction on the different states of IGZO-based devices. In this article, we demonstrate that resistive switching occurs due to the modulation of the Schottky barrier present at the bottom interface of the device. Furthermore, thermionic field emission and field emission regimes are identified as the dominant conduction mechanisms at the high resistive state of the device, while the bulk-limited ohmic conduction is found at the low resistive state. Due to the high complexity associated with creating compact models of resistive switching, a data-driven model is drafted taking systematic steps. (C) 2022 Author(s).

2022

Flexible Active Crossbar Arrays Using Amorphous Oxide Semiconductor Technology toward Artificial Neural Networks Hardware

Authors
Pereira, ME; Deuermeier, J; Figueiredo, C; Santos, A; Carvalho, G; Tavares, VG; Martins, R; Fortunato, E; Barquinha, P; Kiazadeh, A;

Publication
ADVANCED ELECTRONIC MATERIALS

Abstract
Memristor crossbar arrays can compose the efficient hardware for artificial intelligent applications. However, the requirements for a linear and symmetric synaptic weight update and low cycle-to-cycle (C2C) and device-to-device variability as well as the sneak-path current issue have been delaying its further development. This study reports on a thin-film amorphous oxide-based 4x4 1-transistor 1-memristor (1T1M) crossbar. The a-IGZO crossbar is built on a flexible polyimide substrate, enabling IoT and wearable applications. In the novel framework, the thin-film transistor and memristor are fabricated at the same level, with the same processing steps and sharing the same materials for all layers. The 1T1M cells show linear and symmetrical plasticity characteristic with low C2C variability. The memristor performs like an analog dot product engine and vector-matrix multiplications in the 4x4 crossbars is demonstrated experimentally, in which the sneak-path current issue is successfully suppressed, resulting in a proof-of-concept for a cost-effective, flexible artificial neural networks hardware.

2022

All-Standard-Cell-Based Analog-to-Digital Architectures Well-Suited for Internet of Things Applications

Authors
Correia, A; Tavares, VG; Barquinha, P; Goes, J;

Publication
JOURNAL OF LOW POWER ELECTRONICS AND APPLICATIONS

Abstract
In this paper, the most suited analog-to-digital (A/D) converters (ADCs) for Internet of Things (IoT) applications are compared in terms of complexity, dynamic performance, and energy efficiency. Among them, an innovative hybrid topology, a digital-delta (& UDelta;) modulator (& UDelta;M) ADC employing noise shaping (NS), is proposed. To implement the active building blocks, several standard-cell-based synthesizable comparators and amplifiers are examined and compared in terms of their key performance parameters. The simulation results of a fully synthesizable Digital-& UDelta;M with NS using passive and standard-cell-based circuitry show a peak of 72.5 dB in the signal-to-noise and distortion ratio (SNDR) for a 113 kHz input signal and 1 MHz bandwidth (BW). The estimated FoMWalden is close to 16.2 fJ/conv.-step.

2022

Lesion Volume Quantification Using Two Convolutional Neural Networks in MRIs of Multiple Sclerosis Patients

Authors
de Oliveira, M; Piacenti Silva, M; da Rocha, FCG; Santos, JM; Cardoso, JD; Lisboa, PN;

Publication
DIAGNOSTICS

Abstract
Background: Multiple sclerosis (MS) is a neurologic disease of the central nervous system which affects almost three million people worldwide. MS is characterized by a demyelination process that leads to brain lesions, allowing these affected areas to be visualized with magnetic resonance imaging (MRI). Deep learning techniques, especially computational algorithms based on convolutional neural networks (CNNs), have become a frequently used algorithm that performs feature self-learning and enables segmentation of structures in the image useful for quantitative analysis of MRIs, including quantitative analysis of MS. To obtain quantitative information about lesion volume, it is important to perform proper image preprocessing and accurate segmentation. Therefore, we propose a method for volumetric quantification of lesions on MRIs of MS patients using automatic segmentation of the brain and lesions by two CNNs. Methods: We used CNNs at two different moments: the first to perform brain extraction, and the second for lesion segmentation. This study includes four independent MRI datasets: one for training the brain segmentation models, two for training the lesion segmentation model, and one for testing. Results: The proposed brain detection architecture using binary cross-entropy as the loss function achieved a 0.9786 Dice coefficient, 0.9969 accuracy, 0.9851 precision, 0.9851 sensitivity, and 0.9985 specificity. In the second proposed framework for brain lesion segmentation, we obtained a 0.8893 Dice coefficient, 0.9996 accuracy, 0.9376 precision, 0.8609 sensitivity, and 0.9999 specificity. After quantifying the lesion volume of all patients from the test group using our proposed method, we obtained a mean value of 17,582 mm(3). Conclusions: We concluded that the proposed algorithm achieved accurate lesion detection and segmentation with reproducibility corresponding to state-of-the-art software tools and manual segmentation. We believe that this quantification method can add value to treatment monitoring and routine clinical evaluation of MS patients.

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