Abstract
This paper addresses a job shop scheduling problem with peak power constraints, in which jobs can be processed once or multiple times on either all or a subset of the machines. The latter characteristic provides additional flexibility, nowadays present in many manufacturing systems. The problem is complicated by the need to determine both the operation sequence and starting time as well as the speed at which machines process each operation. Due to the adherence to renewable energy production and its intermittent nature, manufacturing companies need to adopt power-flexible production schedules. The proposed power control strategies, that is, adjusting processing speed and timing to reduce peak power requirements may impact production time (makespan) and energy consumption. Therefore, we propose a bi-objective approach that minimizes both objectives. A linear programming model is developed to provide a formal statement of the problem, which is solved to optimality for small-sized instances. We also proposed a multi-objective biased random key genetic algorithm framework that evolves several populations in parallel. Computational experiments provide decision and policymakers with insights into the implications of imposing or negotiating power consumption limits. Finally, the several trade-off solutions obtained show that as the power limit is lowered, the makespan increases at an increasing rate and a similar trend is observed in energy consumption but only for very small makespan values. Furthermore, peak power demand reductions of about 25% have a limited impact on the minimum makespan value (4-6% increase), while at the same time allowing for a small reduction in energy consumption.

Abstract
As many automated algorithms find their way into the IT systems of the banking sector, having a way to validate and interpret the results from these algorithms can lead to a substantial reduction in the risks associated with automation. Usually, validating these pricing mechanisms requires human resources to manually analyze and validate large quantities of data. There is a lack of effective methods that analyze the time series and understand if what is currently happening is plausible based on previous data, without information about the variables used to calculate the price of the asset. This paper describes an implementation of a process that allows us to validate many data points automatically. We explore the K-Nearest Neighbors algorithm to find coincident patterns in financial time series, allowing us to detect anomalies, outliers, and data points that do not follow normal behavior. This system allows quicker detection of defective calculations that would otherwise result in the incorrect pricing of financial assets. Furthermore, our method does not require knowledge about the variables used to calculate the time series being analyzed. Our proposal uses pattern matching and can validate more than 58% of instances, substantially improving human risk analysts' efficiency. The proposal is completely transparent, allowing analysts to understand how the algorithm made its decision, increasing the trustworthiness of the method.

Abstract
The power transformer is one of the key components of any electrical grid, and, as such, modern day industrialization activities require constant usage of the asset. This increases the possibility of failures and can potentially diminish the lifespan of a power transformer. Dissolved gas analysis (DGA) is a technique developed to quantify the existence of hydrocarbon gases in the content of the power transformer oil, which in turn can indicate the presence of faults. Since this process requires different chemical analysis for each type of gas, the overall cost of the operation increases with number of gases. Thus said, a machine learning methodology was defined to meet two simultaneous objectives, identify gas subsets, and predict the remaining gases, thus restoring them. Two subsets of equal or smaller size to those used by traditional methods (Duval's triangle, Roger's ratio, IEC table) were identified, while showing potentially superior performance. The models restored the discarded gases, and the restored set was compared with the original set in a variety of validation tasks.

Abstract
Large language models (LLMs) have substantially pushed artificial intelligence (AI) research and applications in the last few years. They are currently able to achieve high effectiveness in different natural language processing (NLP) tasks, such as machine translation, named entity recognition, text classification, question answering, or text summarization. Recently, significant attention has been drawn to OpenAI's GPT models' capabilities and extremely accessible interface. LLMs are nowadays routinely used and studied for downstream tasks and specific applications with great success, pushing forward the state of the art in almost all of them. However, they also exhibit impressive inference capabilities when used off the shelf without further training. In this paper, we aim to study the behavior of pre-trained language models (PLMs) in some inference tasks they were not initially trained for. Therefore, we focus our attention on very recent research works related to the inference capabilities of PLMs in some selected tasks such as factual probing and common-sense reasoning. We highlight relevant achievements made by these models, as well as some of their current limitations that open opportunities for further research.This article is categorized under:Fundamental Concepts of Data and Knowledge > Key Design Issues in DataMiningTechnologies > Artificial Intelligence

Abstract
The capabilities of the most recent language models have increased the interest in integrating them into real-world applications. However, the fact that these models generate plausible, yet incorrect text poses a constraint when considering their use in several domains. Healthcare is a prime example of a domain where text-generative trustworthiness is a hard requirement to safeguard patient well-being. In this paper, we present Physio, a chat-based application for physical rehabilitation. Physio is capable of making an initial diagnosis while citing reliable health sources to support the information provided. Furthermore, drawing upon external knowledge databases, Physio can recommend rehabilitation exercises and over-the-counter medication for symptom relief. By combining these features, Physio can leverage the power of generative models for language processing while also conditioning its response on dependable and verifiable sources. A live demo of Physio is available at https://physio.inesctec.pt.

Abstract
BackgroundHereditary transthyretin amyloidosis (ATTRv amyloidosis) is an inherited disease, where the study of family history holds importance. This study evaluates the changes of age-of-onset (AOO) and other age-related clinical factors within and among families affected by ATTRv amyloidosis.MethodsWe analysed information from 934 trees, focusing on family, parents, probands and siblings relationships. We focused on 1494 female and 1712 male symptomatic ATTRV30M patients. Results are presented alongside a comparison of current with historical records. Clinical and genealogical indicators identify major changes.ResultsOverall, analysis of familial data shows the existence of families with both early and late patients (1/6). It identifies long familial follow-up times since patient families tend to be diagnosed over several years. Finally, results show a large difference between parent-child and proband-patient relationships (20-30 years).ConclusionsThis study reveals that there has been a shift in patient profile, with a recent increase in male elderly cases, especially regarding probands. It shows that symptomatic patients exhibit less variability towards siblings, when compared to other family members, namely the transmitting ancestors' age of onset. This can influence genetic counselling guidelines.