Abstract
Allocation of jobs to machines and subsequent sequencing each machine is known as job scheduling problem. Classically, both operations are done in a centralized and static/offline structure, considering some assumptions about the jobs and machining environment. Today, with the advent of Industry 4.0, the need to incorporate real-time data in the scheduling decision process is clear and facilitated. Recently, several studies have been conducted on the collection and application of distributed data in real-time of operations, e.g., job scheduling and control. In practice, pure distribution and decentralization is not yet fully realizable because of e.g., transformation complexity and classical resistance to change. This paper studies a combination of decentralized sequencing and central optimum allocation in a lithography job-shop problem. It compares the level of applicability of two decentralized algorithms against the central scheduling. The results show better relative performance of sequencing in stochastic cases. © IFIP International Federation for Information Processing 2017.

Abstract
In this paper, the main complexities related to the modeling of production planning problems of food products are addressed. We start with a deterministic base model and build a road-map on how to incorporate key features of food production planning. The different "ingredients" are organized around the model components to be extended: constraints, objective functions and parameters. We cover issues such as expiry dates, customers' behavior, discarding costs, value of freshness and age-dependent demand. To understand the impact of these "ingredients", we solve an illustrative example with each corresponding model and analyze the changes on the solution structure of the production plan. The differences across the solutions show the importance of choosing a model suitable to the particular business setting, in order to accommodate the multiple challenges present in these industries. Moreover, acknowledging the perishable nature of the products and evaluating the amount and quality of information at hands may be crucial in lowering overall costs and achieving higher service levels. Afterwards, the deterministic base model is extended to deal with an uncertain demand parameter and risk management issues are discussed using a similar illustrative example. Results indicate the increased importance of risk-management in the production planning of perishable food goods.

Abstract
In food supply chain planning, the trade-off between expected profit and risk is emphasized by the perishable nature of the goods that it has to handle. In particular, the risk of spoilage and the risk of revenue loss are substantial when stochastic parameters related to the demand, the consumer behavior, and the spoilage effect are considered. This paper aims to expose and handle this trade-off by developing risk-averse production planning models that incorporate financial risk measures. In particular, the performance of a risk-neutral attitude is compared to the performance of models taking into account the upper partial mean and the conditional value-at-risk. Insights from an illustrative example show the positive impact of the-risk-averse models in operational performance indicators, such as the amount of expired products. Furthermore, through an extensive computational experiment, the advantage of the conditional value-at-risk model is evidenced, as it is able to dominate the solutions from the upper partial mean for the spoilage performance indicator. These advantages are tightly related to a sustainable view of production planning, and they can be achieved at the expense of controlled losses in the expected profit.

Abstract
The pharmaceutical industry operates in a very competitive and regulated market The increased pressure of pharmacies to order fewer products and to receive them more frequently is overcharging the pharmaceutical's distribution network Furthermore, the tight margins and the continuous growth of generic drugs consumption are pressing wholesalers to optimize their supply chains. In order to survive, wholesalers are rethinking their strategies to increase competitiveness. This paper proposes an optimization-simulation approach to address the wholesalers network redesign problem, trading off the operational costs and customer service level. Firstly, at a strategic-tactical level, the supply chain network redesign decisions are optimized via a mixed integer programming model. Here, the number, location, function and capacity of the warehouses, the allocation of customers to the warehouses and the capacity and function of the distribution channels are defined. Secondly, at an operation level, the solution found is evaluated by means of a discrete event simulation model to assess the impact of the redesign in the wholesaler's daily activities. Computational results on a pharmaceutical wholesaler case-study are discussed and the benefits of this solution approach exposed.

Abstract
Joint production and distribution planning at the operational level has received a great deal of attention from researchers. In most industries these processes are decoupled by means of final goods inventory that allow for a separated planning of these tasks. However, for example, in the catering industry, an integrated planning framework tends to be more favorable due to the perishable nature of the products that forces a make-to-order production strategy. So far this planning problem has only been addressed by allowing the batching of orders. The main contribution of this paper is to extend this approach and prove the importance of lot sizing for make-to-order systems when perishability is explicitly considered. The value of considering lot sizing versus batching is further investigated per type of production scenario. Overall, results indicate that lot sizing is able to deliver better solutions than batching. On average, for the improved instances, the cost savings ascend to 6.5% when using lot sizing. The added flexibility of lot sizing allows for a reduction on production setup costs and both fixed and variable distribution costs. The savings derived from lot sizing are enhanced by customer oriented time windows and production systems with non-triangular setups.

Abstract
The United States, Brazil, and Argentina are responsible for 83% of world’s soybean production. Together, they respond to more than 80% of soybean grains and soybean meal exported and for more than 60% of soybean oil exportation. This paper studies the soybean trade of these three major exporters with the top ten commercial partners of each one in order to examine the main factors that influence this relationship. We follow a network analysis approach to evaluate the level of interdependence between exporters and importers. Our research studies the three main soybean products: grain, meal, and oil. The findings seem to indicate that countries prefer importing soybean grains to process inside their borders due to commodity prices and logistics costs.