Abstract
Designing and optimizing HPC applications are difficult and complex tasks, which require mastering specialized languages and tools for performance tuning. As this is incompatible with the current trend to open HPC infrastructures to a wider range of users, the availability of more sophisticated programming languages and tools to assist and automate the design stages is crucial to provide smoothly migration paths towards novel heterogeneous HPC platforms. The ANTAREX project intends to address these issues by providing a tool flow, a Domain Specific Launguage and APIs to provide application's adaptivity and to runtime manage and autotune applications for heterogeneous HPC systems. Our DSL provides a separation of concerns, where analysis, runtime adaptivity, performance tuning and energy strategies are specified separately from the application functionalities with the goal to increase productivity, significantly reduce time to solution, while making possible the deployment of substantially improved implementations. This paper presents the ANTAREX tool flow and shows the impact of optimization strategies in the context of one of the ANTAREX use cases related to personalized drug design. We show how simple strategies, not devised by typical compilers, can substantially speedup the execution and reduce energy consumption. © 2017 IEEE.

Abstract
Designing and optimizing applications for energy-efficient High Performance Computing systems up to the Exascale era is an extremely challenging problem. This paper presents the toolbox developed in the ANTAREX European project for autotuning and adaptivity in energy efficient HPC systems. In particular, the modules of the ANTAREX toolbox are described as well as some preliminary results of the application to two target use cases.(1)

Abstract
The ANTAREX project relies on a Domain Specific Language (DSL) based on Aspect Oriented Programming (AOP) concepts to allow applications to enforce extra functional properties such as energy-efficiency and performance and to optimize Quality of Service (QoS) in an adaptive way. The DSL approach allows the definition of energy-efficiency, performance, and adaptivity strategies as well as their enforcement at runtime through application autotuning and resource and power management. In this paper, we present an overview of the ANTAREX DSL and some of its capabilities through a number of examples, including how the DSL is applied in the context of one of the project use cases. © 2018 IEEE.

Abstract
Directive-drive programming models, such as OpenMP, are one solution for exploiting the potential of multi-core architectures, and enable developers to accelerate software applications by adding annotations on for-type loops and other code regions. However, manual parallelization of applications is known to be a non trivial and time consuming process, requiring parallel programming skills. Automatic parallelization approaches can reduce the burden on the application development side. This paper presents an OpenMP based automatic parallelization compiler, named AutoPar-Clava, for automatic identification and annotation of loops in C code. By using static analysis, parallelizable regions are detected, and a compilable OpenMP parallel code from the sequential version is produced. In order to reduce the accesses to shared memory by each thread, each variable is categorized into the proper OpenMP scoping. Also, AutoPar-Clava is able to support reduction on arrays, which is available since OpenMP 4.5. The effectiveness of AutoPar-Clava is evaluated by means of the Polyhedral Benchmark suite, and targeting a N-cores x86-based computing platform. The achieved results are very promising and compare favorably with closely related auto-parallelization compilers such as Intel C/C++ Compiler (i.e., icc), ROSE, TRACO, and Cetus.

Abstract
The ANTAREX project developed an approach to the performance tuning of High Performance applications based on an Aspect-oriented Domain Specific Language (DSL), with the goal to simplify the enforcement of extra-functional properties in large scale applications. The project aims at demonstrating its tools and techniques on two relevant use cases, one in the domain of computational drug discovery, the other in the domain of online vehicle navigation. In this paper, we present an overview of the project and of its main achievements, as well as of the large scale experiments that have been planned to validate the approach.

Abstract
This article presents Nonio, a modular, easy-to-use, design space exploration framework focused on exploring custom combinations of compiler flags and compiler sequences. We describe the framework and discuss its use with two of the most popular compiler toolchains, GCC and Clang+LLVM. Particularly, we discuss implementation details in the context of flag selection, when using GCC, and phase selection and ordering, when using Clang+LLVM. The framework software organization allows to easily add new components as plug-ins (e.g., an exploration algorithm, an objective metric, integration with another compiler toolchain). The software architecture provides well-defined interfaces, in order to enable seamless composition and interaction between different components. We present, as an example, a use case where we rely on Nonio to obtain custom compiler flags for reducing the execution time and the energy consumption of a C program, in relation to the best predetermined optimization settings provided by the compiler (e.g., -O3). (C) 2019 The Authors. Published by Elsevier B.V.