Abstract

Abstract
Concept-based models naturally lend themselves to the development of inherently interpretable skin lesion diagnosis, as medical experts make decisions based on a set of visual patterns of the lesion. Nevertheless, the development of these models depends on the existence of concept-annotated datasets, whose availability is scarce due to the specialized knowledge and expertise required in the annotation process. In this work, we show that vision-language models can be used to alleviate the dependence on a large number of concept-annotated samples. In particular, we propose an embedding learning strategy to adapt CLIP to the downstream task of skin lesion classification using concept-based descriptions as textual embeddings. Our experiments reveal that vision-language models not only attain better accuracy when using concepts as textual embeddings, but also require a smaller number of concept-annotated samples to attain comparable performance to approaches specifically devised for automatic concept generation. © 2024 IEEE.

Abstract
This paper presents the main contributions of the VCMI Team to the ImageCLEFmedical GANs 2023 task. This task aims to evaluate whether synthetic medical images generated using Generative Adversarial Networks (GANs) contain identifiable characteristics of the training data. We propose various approaches to classify a set of real images as having been used or not used in the training of the model that generated a set of synthetic images. We use similarity-based approaches to classify the real images based on their similarity to the generated ones. We develop autoencoders to classify the images through outlier detection techniques. Finally, we develop patch-based methods that operate on patches extracted from real and generated images to measure their similarity. On the development dataset, we attained an F1-score of 0.846 and an accuracy of 0.850 using an autoencoder-based method. On the test dataset, a similarity-based approach achieved the best results, with an F1-score of 0.801 and an accuracy of 0.810. The empirical results support the hypothesis that medical data generated using deep generative models trained without privacy constraints threatens the privacy of patients in the training data. © 2023 Copyright for this paper by its authors.

Abstract
Deep Learning models are tremendously valuable in several prediction tasks, and their use in the medical field is spreading abruptly, especially in computer vision tasks, evaluating the content in X-rays, CTs or MRIs. These methods can save a significant amount of time for doctors in patient diagnostics and help in treatment planning. However, these models are significantly sensitive to confounders in the training data and generally suffer a performance hit when dealing with out-of-distribution data, affecting their reliability and scalability in different medical institutions. Deep Learning research on Medical datasets may overlook essential details regarding the image acquisition procedure and the preprocessing steps. This work proposes a data-centric approach, exploring the potential of attention maps as a regularisation technique to improve robustness and generalisation. We use image metadata and explore self-attention maps and contrastive learning to promote feature space invariance to image disturbance. Experiments were conducted using Chest X-ray datasets that are publicly available. Some datasets contained information about the windowing settings applied by the radiologist, acting as a source of variability. The proposed model was tested and outperformed the baseline in out-of-distribution data, serving as a proof of concept. © 2023 IEEE.

Abstract

Abstract
In fields that rely on high-stakes decisions, such as medicine, interpretability plays a key role in promoting trust and facilitating the adoption of deep learning models by the clinical communities. In the medical image analysis domain, gradient-based class activation maps are the most widely used explanation methods and the field lacks a more in depth investigation into inherently interpretable models that focus on integrating knowledge that ensures the model is learning the correct rules. A new approach, B-cos networks, for increasing the interpretability of deep neural networks by inducing weight-input alignment during training showed promising results on natural image classification. In this work, we study the suitability of these B-cos networks to the medical domain by testing them on different use cases (skin lesions, diabetic retinopathy, cervical cytology, and chest X-rays) and conducting a thorough evaluation of several explanation quality assessment metrics. We find that, just like in natural image classification, B-cos explanations yield more localised maps, but it is not clear that they are better than other methods' explanations when considering more explanation properties. © 2024 IEEE.