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Publications

Publications by Francesco Renna

2023

Fractal Bilinear Deep Neural Network Models for Gastric Intestinal Metaplasia Detection

Authors
Pedroso, M; Martins, ML; Libânio, D; Dinis-Ribeiro, M; Coimbra, M; Renna, F;

Publication
2023 IEEE EMBS INTERNATIONAL CONFERENCE ON BIOMEDICAL AND HEALTH INFORMATICS, BHI

Abstract
Gastric Intestinal Metaplasia (GIM) is a precancerous gastric lesion and its early detection facilitates patient followup, thus lowering significantly the risk of death by gastric cancer. However, effective screening of this condition is a very challenging task, resulting low intra and inter-observer concordance. Computer assisted diagnosis systems leveraging deep neural networks (DNNs) have emerged as a way to mitigate these ailments. Notwithstanding, these approaches typically require large datasets in order to learn invariance to the extreme variations typically present in Esophagogastroduodenoscopy (EGD) still frames, such as perspective, illumination, and scale. Hence, we propose to combine a priori information regarding texture characteristics of GIM with data-driven DNN solutions. In particular, we define two different models that treat pre-trained DNNs as general features extractors, whose pairwise interactions with a collection of highly invariant local texture descriptors grounded on fractal geometry are computed by means of an outer product in the embedding space. Our experiments show that these models outperform a baseline DNN by a significant margin over several metrics (e.g., area under the curve (AUC) 0.792 vs. 0.705) in a dataset comprised of EGD narrow-band images. Our best model measures double the positive likelihood ratio when compared to a baseline GIM detector.

2020

Deep learning-based methods for individual recognition in small birds

Authors
Ferreira, AC; Silva, LR; Renna, F; Brandl, HB; Renoult, JP; Farine, DR; Covas, R; Doutrelant, C;

Publication
METHODS IN ECOLOGY AND EVOLUTION

Abstract
Individual identification is a crucial step to answer many questions in evolutionary biology and is mostly performed by marking animals with tags. Such methods are well-established, but often make data collection and analyses time-consuming, or limit the contexts in which data can be collected. Recent computational advances, specifically deep learning, can help overcome the limitations of collecting large-scale data across contexts. However, one of the bottlenecks preventing the application of deep learning for individual identification is the need to collect and identify hundreds to thousands of individually labelled pictures to train convolutional neural networks (CNNs). Here we describe procedures for automating the collection of training data, generating training datasets, and training CNNs to allow identification of individual birds. We apply our procedures to three small bird species, the sociable weaverPhiletairus socius,the great titParus majorand the zebra finchTaeniopygia guttata, representing both wild and captive contexts. We first show how the collection of individually labelled images can be automated, allowing the construction of training datasets consisting of hundreds of images per individual. Second, we describe how to train a CNN to uniquely re-identify each individual in new images. Third, we illustrate the general applicability of CNNs for studies in animal biology by showing that trained CNNs can re-identify individual birds in images collected in contexts that differ from the ones originally used to train the CNNs. Finally, we present a potential solution to solve the issues of new incoming individuals. Overall, our work demonstrates the feasibility of applying state-of-the-art deep learning tools for individual identification of birds, both in the laboratory and in the wild. These techniques are made possible by our approaches that allow efficient collection of training data. The ability to conduct individual recognition of birds without requiring external markers that can be visually identified by human observers represents a major advance over current methods.

2023

Evaluation of automatic pericardial segmentation methods in computed tomography images

Authors
Pedrosa, J; Silva, R; Santos, C; Nunes, F; Mancio, J; Renna, F; Fontes Carvalho, R;

Publication
European Heart Journal - Cardiovascular Imaging

Abstract

2023

Construction of an Algorithm for Three-Dimensional Bone Segmentation from Images Obtained by Computational Tomography

Authors
Barbosa, M; Renna, F; Dourado, N; Costa, R;

Publication
Studies in Computational Intelligence

Abstract
This paper proposes a tool that extracts data from computational tomography (CT) scans of long bones, applies filters to allow a distinction between cortical and cancellous tissue, and converts the tissues into a three-dimensional (3D) model that can be used to generate finite element meshes. In order to identify the best segmentation technique for the problem under study, cortical, cancellous and medulla tissue segmentation was tested based on image histogram information, simple Hounsfield scale (HU) information, HU scale information with morphological operator filters, and active contour methods (active contour, random walker segmentation and findContours). These segmentations were evaluated qualitatively through a visual comparison and quantitatively through the calculation of the Dice Coefficient (DICE) and Mean-Squared Error (MSE) parameters. The developed algorithm presents a Dice higher than 0.95 and a MSE lower than 0.01 for cortical tissue segmentation, which allows it to be used as a bone characterization method. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.

2023

Cross-Domain Detection of Pulmonary Hypertension in Human and Porcine Heart Sounds

Authors
Gaudio, A; Giordano, N; Coimbra, MT; Kjaergaard, B; Schmidt, SE; Renna, F;

Publication
Computing in Cardiology, CinC 2023, Atlanta, GA, USA, October 1-4, 2023

Abstract

2023

Diagnostic Performance of Deep Learning Models for Gastric Intestinal Metaplasia Detection in Narrow-band Images

Authors
Martins, ML; Pedroso, M; Libânio, D; Dinis Ribeiro, M; Coimbra, M; Renna, F;

Publication
2023 45TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY, EMBC

Abstract
Gastric Intestinal Metaplasia (GIM) is one of the precancerous conditions in the gastric carcinogenesis cascade and its optical diagnosis during endoscopic screening is challenging even for seasoned endoscopists. Several solutions leveraging pre-trained deep neural networks (DNNs) have been recently proposed in order to assist human diagnosis. In this paper, we present a comparative study of these architectures in a new dataset containing GIM and non-GIM Narrow-band imaging still frames. We find that the surveyed DNNs perform remarkably well on average, but still measure sizeable interfold variability during cross-validation. An additional ad-hoc analysis suggests that these baseline architectures may not perform equally well at all scales when diagnosing GIM.

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