Abstract
Nowadays achieving sustainable development is a global concern. Economic and environmental sustainability can be driven by assessing and improving industrial production system’s performance. An evaluation that assesses if materials, energy and resources are used to their full potential is a powerful tool for improving economic and environmental performance, and consequently supports the identification of all types of waste and inefficiencies along the production system. The goal of this work is to assess overall production system’s efficiency and eco-efficiency using Multi Layer Stream Mapping (MSM). The outputs of this approach is used to scrutinize “where” and “how much” can a unit process and/or a production system improve its financial, environmental and overall efficiency, thereby being of great importance for decision-making and correct implementation of improvement actions. This paper highlights the results from the application of the MSM methodology in a real industrial case regarding a painting unit.

Abstract
Industrial Symbiosis (IS) envisages a collaborative approach to resource efficiency, encouraging companies to recover, reprocess and reuse waste within the industrial network. Several challenges regarding the effective application of IS continue to limit a broader implementation of this area of Industrial Ecology. The MAESTRI project encompasses an Industrial Symbiosis approach within the scope of sustainable manufacturing for process industries that fosters the sharing of resources (energy, water, residues, etc.) between different processes of a single company or between multiple companies. The Industrial Symbiosis approach is integrated with Efficiency Framework in the so-called MAESTRI Total Efficiency Framework. Efficiency Framework is devoted to the combination of eco-efficiency (via ecoPROSYS) and the efficiency assessment (via MSM - Multi-Layer Stream Mapping). In this manuscript the benefit of the combination of the Efficiency Framework as an facilitator to a more effective application of Industrial Symbiosis, within or outside the company's boundaries, is explored.

Abstract
Nowadays achieving sustainable development is a global concern. Economic and environmental sustainability can be driven by assessing and improving industrial production system's performance. An evaluation that assesses if materials, energy and resources are used to their full potential is a powerful tool for improving economic and environmental performance, and consequently supports the identification of all types of waste and inefficiencies along the production system. The goal of this work is to assess overall production system's efficiency and eco-efficiency using Multi Layer Stream Mapping (MSM). The outputs of this approach is used to scrutinize "where" and "how much" can a unit process and/or a production system improve its financial, environmental and overall efficiency, thereby being of great importance for decision-making and correct implementation of improvement actions. This paper highlights the results from the application of the MSM methodology in a real industrial case regarding a painting unit.

Abstract
Resource efficiency is a crucial step for manufacturing companies to improve their operations performance and to reduce waste generation. However, there is no guarantee of a zero waste scenario and companies need to look for new strategies to complement their resource efficiency vision. Therefore, it is important to enroll in an industrial symbiosis strategy as a means to maximize industrial value capturing through the exchange of resources (waste, energy, water and by-products) between different processes and companies. Within this, it is crucial to quantify and characterize the waste, e.g. to have clear understanding of the potential industrial symbiosis hot spots among the processes. For such characterization, it is proposed to use an innovative process efficiency assessment approach. This empowers a clear understanding and quantification of efficiency that identifies industrial symbiosis hot spots (donors) in low efficiency process steps, and enables a plausible definition of potential cold spots (receivers), in order to promote the symbiotic exchanges. (C) 2018 The Authors. Published by Elsevier B.V.

Abstract
Design-for-X (DfX) approaches are of great importance to support sustainable development of new products, since the goal of DfX practices is to improve life cycle cost, life cycle environmental performance, increase design flexibility, manufacturing efficiency, etc. Therefore DfX supports a better decision-making process whenever a new complex product is being developed. In this work the new Lean Design-for-X (LDfX) approach is presented embracing the principles of Lean Product Development and Modular Design, for a systematic applicability by design engineers and product managers, assessing the effectiveness and efficiency of a given product design. An LDfX index metric, ranging between 0-100%, and original scorecard were created for consistent decision support for the comparison of different design concepts or products, integrating different "X" domains. The approach was applied in a real design study of a machine tool (press-brake), integrating Ecodesign principles, Design for Structural Optimization and Modular Design. (C) 2018 The Authors. Published by Elsevier B.V.

Abstract
The MAESTRI Total Efficient Framework (MTEF) is a recent holistic concept that congregates four complementary dimensions: Efficiency Framework; IoT Platform; Management System and Industrial Symbiosis. MTEF promotes the development of strategies for continuous performance improvement towards a more sustainable manufacturing. The Efficiency Framework supports the integrated assessment of operations efficiency and eco-efficiency, being measured by a new concept: Total Efficiency Index (TEI). The simultaneous assessment of the environmental, economic and efficiency performance of complex production systems is only possible with a digitalized production system, which is aligned with Industry 4.0 paradigm. Thus, with TEI original dashboards and graphical diagram, both static and dynamic assessments of efficiency vs. eco-efficiency can be analyzed. This paper details the fundaments of the Efficiency Framework and TEI, and presents an application case study from the metalworking sector, where the achieved results are discussed for the new concept validation. (C) 2018 The Authors. Published by Elsevier B.V.