2014
Authors
Facao, M; Carvalho, MI;
Publication
APPLIED PHYSICS B-LASERS AND OPTICS
Abstract
Frequency blueshifting was recently observed in light pulses propagating on gas-filled hollow-core photonic crystal fibers where a plasma has been produced due to photoionization of the gas. One of the propagation models that is adequate to describe the actual experimental observations is here investigated. It is a nonlinear Schrodinger equation with an extra term, to which we applied a self-similar change of variables and found its accelerating solitons. As in other NLS-related models possessing accelerating solitons, there exist asymmetrical pulses that decay as they propagate in some parameter region that was here well defined.
2015
Authors
Oliveira, LM; Carvalho, MI; Nogueira, EM; Tuchin, VV;
Publication
JOURNAL OF BIOMEDICAL OPTICS
Abstract
Part of the optical clearing study in biological tissues concerns the determination of the diffusion characteristics of water and optical clearing agents in the subject tissue. Such information is sufficient to characterize the time dependence of the optical clearing mechanisms-tissue dehydration and refractive index (RI) matching. We have used a simple method based on collimated optical transmittance measurements made from muscle samples under treatment with aqueous solutions containing different concentrations of ethylene glycol (EG), to determine the diffusion time values of water and EG in skeletal muscle. By representing the estimated mean diffusion time values from each treatment as a function of agent concentration in solution, we could identify the real diffusion times for water and agent. These values allowed for the calculation of the correspondent diffusion coefficients for those fluids. With these results, we have demonstrated that the dehydration mechanism is the one that dominates optical clearing in the first minute of treatment, while the RI matching takes over the optical clearing operations after that and remains for a longer time of treatment up to about 10 min, as we could see for EG and thin tissue samples of 0.5 mm. (C) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
2018
Authors
Oliveira, LM; Carvalho, MI; Nogueira, EM; Tuchin, VV;
Publication
JOURNAL OF BIOPHOTONICS
Abstract
Skeletal muscle dispersion and optical clearing (OC) kinetics were studied experimentally to prove the existence of the refractive index (RI) matching mechanism of OC. Sample thickness and collimated transmittance spectra were measured during treatments with glucose (40%) and ethylene glycol (EG; 99%) solutions and used to obtain the time dependence of the RI of tissue fluids based on the proposed theoretical model. Calculated results demonstrated an increase of RI of tissue fluids and consequently proved the occurrence of the RI matching mechanism. The RI increase was observed for the wavelength range between 400 and 1000 nm and for the 2 probing molecules explored. We found that for 30 min treatment with 40% glucose and 99% EG, RI of sarcoplasm plus interstitial fluid was increased at 800 nm from 1.328 to 1.348 and from 1.328 to 1.369, respectively.
2013
Authors
Facao, M; Carvalho, MI; Almeida, P;
Publication
PHYSICAL REVIEW A
Abstract
We found the self-similar solitary solutions of a recently proposed model for the propagation of pulses in gas-filled hollow-core photonic crystal fibers that includes a plasma induced nonlinearity. As anticipated for a simpler model and using a perturbation analysis, there are indeed stationary solitary waves that accelerate and self-shift to higher frequencies. However, if the plasma nonlinearity strength is large or the pulse amplitudes are small, the solutions have distinguished long tails and decay as they propagate.
2015
Authors
Facao, M; Carvalho, MI;
Publication
PHYSICAL REVIEW E
Abstract
We found two stationary solutions of the cubic complex Ginzburg-Landau equation (CGLE) with an additional term modeling the delayed Raman scattering. Both solutions propagate with nonzero velocity. The solution that has lower peak amplitude is the continuation of the chirped soliton of the cubic CGLE and is unstable in all the parameter space of existence. The other solution is stable for values of nonlinear gain below a certain threshold. The solutions were found using a shooting method to integrate the ordinary differential equation that results from the evolution equation through a change of variables, and their stability was studied using the Evans function method. Additional integration of the evolution equation revealed the basis of attraction of the stable solutions. Furthermore, we have investigated the existence and stability of the high amplitude branch of solutions in the presence of other higher order terms originating from complex Raman, self-steepening, and imaginary group velocity.
2013
Authors
Oliveira, L; Carvalho, MI; Nogueira, E; Tuchin, VV;
Publication
JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES
Abstract
With the objective to study the variation of optical properties of rat muscle during optical clearing, we have performed a set of optical measurements from that kind of tissue. The measurements performed were total transmittance, collimated transmittance, specular reflectance and total reflectance. This set of measurements is sufficient to determine diffuse reflectance and absorbance of the sample, also necessary to estimate the optical properties. All the performed measurements and calculated quantities will be used later in inverse Monte Carlo (IMC) simulations to determine the evolution of the optical properties of muscle during treatments with ethylene glycol and glucose. The results obtained with the measurements already provide some information about the optical clearing treatments applied to the muscle and translate the mechanisms of turning the tissue more transparent and sequence of regimes of optical clearing.
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