Abstract
Breast cancer patients often face difficulties when choosing among diverse surgeries. To aid patients, this paper proposes ACID-GAN (Anatomically and Clinically Informed Deep Generative Adversarial Network), a conditional generative model for predicting post-operative breast cancer outcomes using deep learning. Built on Pix2Pix, the model incorporates clinical metadata, such as surgery type and cancer laterality, by introducing a dedicated encoder for semantic supervision. Further improvements include colour preservation and anatomically informed losses, as well as clinical supervision via segmentation and classification modules. Experiments on a private dataset demonstrate that the model produces realistic, context-aware predictions. The results demonstrate that the model presents a meaningful trade-off between generating precise, anatomically defined results and maintaining patient-specific appearance, such as skin tone and shape.

Abstract
We study the optimal online service for grocery retailers operating both physical and online stores. The challenge lies in optimizing the size of the online assortment and the delivery fees to maximize profitability across channels, while considering customer, operational, and market dynamics. Using transaction data from a major grocery retailer, we employ an alternative-specific conditional logit model to investigate how delivery fees, assortment size, network characteristics, and customer needs influence store choice and spending across physical and online channels. We develop a profitability model that incorporates online service variables, customer behavior, and operational costs, enabling us to explore optimal strategies under various conditions. By identifying favorable conditions for the online store and analyzing optimal service variables, we provide actionable insights for retailers. Our findings challenge common practices in omnichannel retail. We show that delivery fees should not merely cover costs but can be strategically set higher, particularly for retailers with strong offline presence. Additionally, while reducing fulfillment costs improves profitability, its impact is smaller than expected. Multichannel retailers can offset these costs by passing them on to customers, with minimal overall demand loss, as some customers opt to shop in physical stores rather than abandoning the retailer entirely. Lastly, maximizing the online assortment may not always be optimal, particularly if the operational inefficiencies and costs outweigh the value customers place on variety. Our methodological framework provides retailers the opportunity to align their online services with customer preferences and operational constraints and to leverage customer data in shaping their omnichannel strategies. © 2026 The Author(s)

Abstract
Breast cancer locoregional treatment includes a wide variety of procedures with diverse aesthetic outcomes. The aesthetic assessment of such procedures is typically subjective, hindering the fair comparison between their outcomes, and consequently restricting evidence-based improvements. Most objective evaluation tools were developed for conservative surgery, focusing on asymmetries while ignoring other relevant traits. To overcome these limitations, we propose SiameseOrdinalCLIP, an ordinal classification network based on image-text matching and pairwise ranking optimisation for the aesthetic evaluation of breast cancer treatment. Furthermore, we integrate a concept bottleneck module into the network for increased explainability. Experiments on a private dataset show that the proposed model surpasses the state-of-the-art aesthetic evaluation and ordinal classification networks.

Abstract
As technology continues to evolve, organizations face growing and complex challenges and opportunities that affect their ability to govern, manage and harness data as a key source of competitive advantage. Equally, data are considered a powerful and unique source of success for organizations, which in turn, can impact their decision-making capabilities and play a critical role in their success. Hence, this article aims to provide a detailed identification, analysis and discussion over the current data governance context and its existing frameworks, highlighting their commonalities, differences and gaps, including ones related to data governance relationship with Generative Artificial Intelligence (GenAI). This article conducts an extensive methodological and in-depth analysis over a set of sixteen data governance frameworks based on different key data governance attributes, denoting that although there are numerous frameworks, they hold weaknesses, limitations and challenges which prevent them from being capable of incorporating and governing the use and management of AI, particularly the demands originating from GenAI. Our findings provide and propose a new and enhanced data governance framework which integrates the best features and ideas from the existing ones and initiatives derived from the advancements and particularities of AI and GenAI models, systems, and overall usage.

Abstract
In addition to evaluating tumor morphology using H&E staining, immunohistochemistry is used to assess the presence of specific proteins within the tissue. However, this is a costly and labor-intensive technique, for which virtual staining, as an image-to-image translation task, offers a promising alternative. Although recent, this is an emerging field of research with 64% of published studies just in 2024. Most studies use publicly available datasets of H&E-IHC pairs from consecutive tissue sections. Recognizing the training challenges, many authors develop complex virtual staining models based on conditional Generative Adversarial Networks but ignore the impact of adversarial loss on the quality of virtual staining. Furthermore, overlooking the issues of model evaluation, they claim improved performance based on metrics such as SSIM and PSNR, which are not sufficiently robust to evaluate the quality of virtually stained images. In this paper, we developed CSSP2P GAN, which we demonstrate to achieve heightened pathological fidelity through a blind pathological expert evaluation. Furthermore, while iteratively developing our model, we study the impact of the adversarial loss and demonstrate its crucial role in the quality of virtually stained images. Finally, while comparing our model with reference works in the field, we underscore the limitations of the currently used evaluation metrics and demonstrate the superior performance of CSSP2P GAN.

Abstract
This work reflects upon what Immersion can mean from the perspective of an Artificial Intelligence (AI). Applying the lens of immersive learning theory, it seeks to understand whether this new perspective supports ways for AI participation in cognitive ecologies. By treating AI as a participant rather than a tool, it explores what other participants (humans and other AIs) need to consider in environments where AI can meaningfully engage and contribute to the cognitive ecology, and what the implications are for designing such learning environments. Drawing from the three conceptual dimensions of immersion-System, Narrative, and Agency-this work reinterprets AIs in immersive learning contexts. It outlines practical implications for designing learning environments where AIs are surrounded by external digital services, can interpret a narrative of origins, changes, and structural developments in data, and dynamically respond, making operational and tactical decisions that shape human-AI collaboration. Finally, this work suggests how these insights might influence the future of AI training, proposing that immersive learning theory can inform the development of AIs capable of evolving beyond static models. This paper paves the way for understanding AI as an immersive learner and participant in evolving human-AI cognitive ecosystems.