Abstract
Histology is a preclinical subject transversal in medical, dental, and veterinary curricula. Classical teaching approaches in histology are often undermined by lower motivation and engagement of students, which may be addressed by innovative learning environments. Herein, we developed a serious game approach and compared it with a classical teaching style. The students' feedback was evaluated by questionnaires, and their performance on quizzes and exam's scores were assessed. The serious game (Histopoly) consisted of a game-based web application for the teacher/game master, a digital gaming application used by the students as a controller, and a projected digital board game. The board featured rows for the four fundamental tissues (epithelial, connective, muscular, and nervous) paired with question tiles and additional tiles with more demanding activities (e.g., drawing, presenting slides, and making a syllabus). Participants included all veterinary students enrolled in the first year. Paired laboratory sessions were split with four sections (n = 94 students) playing Histopoly at the end of all sessions and two sections (n = 28 students) completing small evaluations every three weeks at the beginning of sessions. According to the questionnaires, students that played the serious game were more motivated, engaged, and more interconnected with classmates. The activity was considered fun, and students enjoyed the classes more. No differences in the final examination scores were found, but the percentage of correct answers provided throughout the serious game was significantly higher. Overall, these findings argue for the inclusion of serious games in modern histology teaching to promote student engagement in learning.

Abstract
Prognosis after intracranial hemorrhage (ICH) is influenced by a complex interplay between imaging and tabular data. Rapid and reliable prognosis are crucial for effective patient stratification and informed treatment decision-making. In this study, we aim to enhance image-based prognosis by learning a robust feature representation shared between prognosis and the clinical and demographic variables most highly correlated with it. Our approach mimics clinical decision-making by reinforcing the model to learn valuable prognostic data embedded in the image. We propose a 3D multi-task image model to predict prognosis, Glasgow Coma Scale and age, improving accuracy and interpretability. Our method outperforms current state-of-the-art baseline image models, and demonstrates superior performance in ICH prognosis compared to four board-certified neuroradiologists using only CT scans as input. We further validate our model with interpretability saliency maps. Code is available at https://github.com/MiriamCobo/MultitaskLearning_ICH_Prognosis.git.

Abstract
The potential of Augmented Reality (AR) has been harnessed to create immersive game settings, present layers of relevant information in museums, streamline procedures in healthcare and industry, and captivate consumers through innovative marketing strategies. Certain artifacts lend themselves well to representation in AR, especially those requiring a seamless fusion of the information layer with physical space. This integration underscores the suitability of information design artifacts for AR implementation. This study aims to delineate the distinctive attributes of AR in remediating information design, effectively catering to the user’s informational needs. To this end, we analyzed the Google Translate app, examining it through the analytical lens of body schema and haptic engagement. The findings reveal that AR manifests as a performative, personalized, crafted image that fosters involvement through agency. The performative nature of the image directs attention, while individual images collectively form a collection. It is recommended that AR design be centered around achieving harmony among body, media, and space. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

Abstract
The autonomous navigation of unmanned ground vehicles (UGVs) in unstructured environments, such as agricultural or forestry settings, has been the subject of extensive research by various investigators. The navigation capability of a UGV in unstructured environments requires considering numerous factors, including the quality of data reception that allows reliable interpretation of what the UGV perceives in a given environment, as well as the use these data to control the UGV's navigation. This article aims to study different PID control algorithms to enable autonomous navigation on a robotic platform. The robotic platform consists of a forestry tractor, used for forest cleaning tasks, which was converted into a UGV through the integration of sensors. Using sensor data, the UGV's position and orientation are obtained and utilized for navigation by inputting these data into a PID control algorithm. The correct choice of PID control algorithm involved the study, analysis, and implementation of different controllers, leading to the conclusion that the Vector Field control algorithm demonstrated better performance compared to the others studied and implemented in this paper.

Abstract
Most human time is spent indoors, and due to the pandemic, monitoring indoor air quality (IAQ) has become more crucial. In this study, an IoT (Internet of Things) architecture is implemented to monitor IAQ parameters, including CO2 and particulate matter (PM). An ESP32-C6-based device is developed to measure sensor data and send them, using the MQTT protocol, to a remote InfluxDBv2 database instance, where the data are stored and visualized. The Python 3.11 scripting programming language is used to automate Flux queries to the database, allowing a more in-depth data interpretation. The implemented system allows to analyze two measured scenarios during sleep: one with the door slightly open and one with the door closed. Results indicate that sleeping with the door slightly open causes CO2 levels to ascend slowly and maintain lower concentrations compared to sleeping with the door closed, where CO2 levels ascend faster and the maximum recommended values are exceeded. This demonstrates the benefits of ventilation in maintaining IAQ. The developed system can be used for sensing in different environments, such as schools or offices, so an IAQ assessment can be made. Based on the generated data, predictive models can be designed to support decisions on intelligent natural ventilation systems, achieving an optimized, efficient, and ubiquitous solution to moderate the IAQ.

Abstract
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by hyperglycemia, which could alter metabolic, vascular and hematological parameters. A low-carbohydrate, high-fat diet (LCHF) diet benefits glycemic and blood pressure control. In turn, exercise in hypoxia (EH) is known to improve insulin sensitivity, erythropoiesis and angiogenesis. LCHF combined with EH seem to be a potential therapeutic strategy for T2DM and hypertension (HTN), but evidence is still scarce. The aim of this study was to evaluate the effects of eight weeks of EH combined with a LCHF on hematological and lipid profiles, inflammation and blood pressure in older patients with T2DM and coexistent HTN. Diabetic patients with HTN (n=42) were randomly assigned to a (1) control group: control diet (high-carbohydrate and low-fat diet) + exercise in normoxia; (2) EH group: control diet + EH; (3) intervention group: LCHF + EH. Baseline and eight-week measurements included systolic, diastolic, and mean blood pressure (SBP, DBP, MAP, respectively), and hematological and lipid profiles and inflammation biomarkers. Blood pressure decreased after interventions (p<0.001), with no differences among groups (SBP: p=0.151; DBP: p=0.124 and MAP: p=0.18). There were no differences in lipid profile and C-reactive protein (p>0.05). Mean corpuscular hemoglobin (MCH) increased in the EH group (p=0.027), while MCH concentration decreased in the EH+LCHF group (p=0.046). In conclusion, there is no additional benefit in adding hypoxia to exercise or restricting carbohydrates, on blood pressure in patients with T2DM and coexisting HTN. Further elucidation of the mechanisms underlying hematological adaptations is imperative. Trial registration number: NCT05094505.