Abstract
Introduction: Breast volume estimation is considered crucial for breast cancer surgery planning. A single, easy, and reproducible method to estimate breast volume is not available. This study aims to evaluate, in patients proposed for mastectomy, the accuracy of the calculation of breast volume from a low-cost 3D surface scan (Microsoft Kinect) compared to the breast MRI and water displacement technique. Material and Methods: Patients with a Tis/T1-T3 breast cancer proposed for mastectomy between July 2015 and March 2017 were assessed for inclusion in the study. Breast volume calculations were performed using a 3D surface scan and the breast MRI and water displacement technique. Agreement between volumes obtained with both methods was assessed with the Spearman and Pearson correlation coefficients. Results: Eighteen patients with invasive breast cancer were included in the study and submitted to mastectomy. The level of agreement of the 3D breast volume compared to surgical specimens and breast MRI volumes was evaluated. For mastectomy specimen volume, an average (standard deviation) of 0.823 (0.027) and 0.875 (0.026) was obtained for the Pearson and Spearman correlations, respectively. With respect to MRI annotation, we obtained 0.828 (0.038) and 0.715 (0.018). Discussion: Although values obtained by both methodologies still differ, the strong linear correlation coefficient suggests that 3D breast volume measurement using a low-cost surface scan device is feasible and can approximate both the MRI breast volume and mastectomy specimen with sufficient accuracy. Conclusion: 3D breast volume measurement using a depth-sensor low-cost surface scan device is feasible and can parallel MRI breast and mastectomy specimen volumes with enough accuracy. Differences between methods need further development to reach clinical applicability. A possible approach could be the fusion of breast MRI and the 3D surface scan to harmonize anatomic limits and improve volume delimitation.

Abstract

Abstract
The coronavirus disease 2019 (COVID-19) evolved into a global pandemic, responsible for a significant number of infections and deaths. In this scenario, point-of-care ultrasound (POCUS) has emerged as a viable and safe imaging modality. Computer vision (CV) solutions have been proposed to aid clinicians in POCUS image interpretation, namely detection/segmentation of structures and image/patient classification but relevant challenges still remain. As such, the aim of this study is to develop CV algorithms, using Deep Learning techniques, to create tools that can aid doctors in the diagnosis of viral and bacterial pneumonia (VP and BP) through POCUS exams. To do so, convolutional neural networks were designed to perform in classification tasks. The architectures chosen to build these models were the VGG16, ResNet50, DenseNet169 e MobileNetV2. Patients images were divided in three classes: healthy (HE), BP and VP (which includes COVID-19). Through a comparative study, which was based on several performance metrics, the model based on the DenseNet169 architecture was designated as the best performing model, achieving 78% average accuracy value of the five iterations of 5- Fold Cross-Validation. Given that the currently available POCUS datasets for COVID-19 are still limited, the training of the models was negatively affected by such and the models were not tested in an independent dataset. Furthermore, it was also not possible to perform lesion detection tasks. Nonetheless, in order to provide explainability and understanding of the models, Gradient-weighted Class Activation Mapping (GradCAM) were used as a tool to highlight the most relevant classification regions. Clinical relevance - Reveals the potential of POCUS to support COVID-19 screening. The results are very promising although the dataset is limite

Abstract
BackgroundTraumatic Brain Injury (TBI) is one of the leading causes of injury related mortality in the world, with severe cases reaching mortality rates of 30-40%. It is highly heterogeneous both in causes and consequences, complicating medical interpretation and prognosis. Gathering clinical, demographic, and laboratory data to perform a prognosis requires time and skill in several clinical specialties. Machine learning (ML) methods can take advantage of the data and guide physicians toward a better prognosis and, consequently, better healthcare. The objective of this study was to develop and test a wide range of machine learning models and evaluate their capability of predicting mortality of TBI, at hospital discharge, while assessing the similarity between the predictive value of the data and clinical significance. MethodsThe used dataset is the Hackathon Pediatric Traumatic Brain Injury (HPTBI) dataset, composed of electronic health records containing clinical annotations and demographic data of 300 patients. Four different classification models were tested, either with or without feature selection. For each combination of the classification model and feature selection method, the area under the receiver operator curve (ROC-AUC), balanced accuracy, precision, and recall were calculated. ResultsMethods based on decision trees perform better when using all features (Random Forest, AUC = 0.86 and XGBoost, AUC = 0.91) but other models require prior feature selection to obtain the best results (k-Nearest Neighbors, AUC = 0.90 and Artificial Neural Networks, AUC = 0.84). Additionally, Random Forest and XGBoost allow assessing the feature's importance, which could give insights for future strategies on the clinical routine. ConclusionPredictive capability depends greatly on the combination of model and feature selection methods used but, overall, ML models showed a very good performance in mortality prediction for TBI. The feature importance results indicate that predictive value is not directly related to clinical significance.

Abstract
Nowadays, a laboratory operator in the areas of chemistry, biology or medicine spends considerable time performing micropipetting procedures, a common, monotonous and repetitive task which compromises the ergonomics of individuals, namely related to wrist musculoskeletal disorders. In this work, the design of a kinesthetic teaching approach for automating the micropipetting technique is presented, allowing to redirect the operator to other non-repetitive tasks, aiming to reduce the exposure to ergonomic risks. The proposed robotic solution has an innovative gripping system capable of supporting, actuating and regulating the volume of a manual micropipette. The system is able to configure the position of diverse laboratory materials, such as lab containers and plates, on the workbench through a collaborative robotic arm, providing flexibility to adapt to different procedures. A projected human-machine interface, which combines the display of information on the workbench with an infrared based interaction device was developed, providing a more intuitive interaction between the operator and the system during the configuration and operation phases. In contrast to the majority of the existing liquid handling systems, the proposed system allows the operator to place the materials freely on the workbench and the usage of different materials' variants, facilitating the implementation of the system in any laboratory. The attained performance and ease of use of the system were very encouraging since all the defined tasks in the conducted experiments were successfully performed by users with minimum training, highlighting its potential inclusion in the laboratory routine panorama.

Abstract
Over the years, the evolution of face recognition (FR) algorithms has been steep and accelerated by a myriad of factors. Motivated by the unexpected elements found in real-world scenarios, researchers have investigated and developed a number of methods for occluded face recognition (OFR). However, due to the SarS-Cov2 pandemic, masked face recognition (MFR) research branched from OFR and became a hot and urgent research challenge. Due to time and data constraints, these models followed different and novel approaches to handle lower face occlusions, i.e., face masks. Hence, this study aims to evaluate the different approaches followed for both MFR and OFR, find linked details about the two conceptually similar research directions and understand future directions for both topics. For this analysis, several occluded and face recognition algorithms from the literature are studied. First, they are evaluated in the task that they were trained on, but also on the other. These methods were picked accordingly to the novelty of their approach, proven state-of-the-art results, and publicly available source code. We present quantitative results on 4 occluded and 5 masked FR datasets, and a qualitative analysis of several MFR and OFR models on the Occ-LFW dataset. The analysis presented, sustain the interoperable deployability of MFR methods on OFR datasets, when the occlusions are of a reasonable size. Thus, solutions proposed for MFR can be effectively deployed for general OFR.