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Publications

Publications by BIO

2012

A winner shoe in the motor

Authors
Al Rawi, MS; Silva Cunha, JPS;

Publication
JOURNAL OF NEUROLOGY

Abstract

2012

A novel non-invasive continuous system for estimating arterial blood pressure: first-in-man clinical results

Authors
Bras, S; Ribeiro, D; Silva Cunha, JPS; Fontes Carvalho, R;

Publication
EUROPEAN HEART JOURNAL

Abstract

2011

Non-contact Pulse Wave Velocity Assessment Using Optical Methods

Authors
Pereira, T; Cabeleira, M; Matos, P; Borges, E; Almeida, V; Pereira, HC; Cardoso, J; Correia, CMBA;

Publication
Biomedical Engineering Systems and Technologies - 4th International Joint Conference, BIOSTEC 2011, Rome, Italy, January 26-29, 2011, Revised Selected Papers

Abstract
The clinical relevance of pulse wave velocity (PWV), as an indicator of cardiac risk associated to arterial stiffness, has gained clinical relevance over the last years. Optic sensors are an attractive instrumental solution for this type of measurement due to their truly non-contact operation capability, which has the potential of an interference free measurement. The nature of the optically originated signals, however, poses new challenges to the designer, either at the probe design level as at the signal processing required to extract the timing information that yields PWV. In this work we describe the construction of two prototype optical probes and discuss their evaluation using three algorithms for pulse transit time (PTT) evaluation. Results, obtained in a dedicated test bench, that is also described, demonstrate the possibility of measuring pulse transit times as short as 1ms with less than 1% error. © Springer-Verlag Berlin Heidelberg 2013.

2011

Signal analysis in a new optical pulse waveform profiler for cardiovascular applications

Authors
Pereira, T; Oliveira, T; Cabeleira, M; Matos, P; Pereira, HC; Almeida, V; Borges, E; Santos, H; Pereira, T; Cardoso, J; Correia, C;

Publication
Proceedings of the IASTED International Conference on Signal and Image Processing and Applications, SIPA 2011

Abstract
Sub-millimetre distension waveforms (0.7 mm, max) are assessed using two new optical probes. The probes differ on the type of photo-detector used: planar photodiodes (PPD), in one case, and avalanche photodiodes (APD), in the other. Performance of the probes is evaluated in an especially developed test setup and in vivo, at the carotid site of humans. In the latter case, distension (associated to the pressure wave generated by the left ventricle contraction that propagates through the arterial system) carries clinically relevant information that can be extracted if, as will be shown, the waveforms are accurate and have enough resolution. An ultrasound image system, Vivid" e, was used as source of reference data for comparison. Along with the probes, a set of software routines was also developed to extract artefact-free data and evaluate the error. Results from the test setup demonstrate the possibility of waveform distension measurements with less than 6% error for both optical probes in this study. In comparison with an ultrasound system, the optical sensors allow the reproduction of the arterial waveform with a higher resolution, adequate to feed feature extraction algorithms.

2011

A cardiac signal monitoring and processing system

Authors
Almeida, VG; Pereira, TM; Pereira, HC; Cardoso, JMR; Correia, C;

Publication
1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011

Abstract
The social and economic impact of cardiovascular diseases and the importance of efficient early diagnostic tools are self-evident. This project finds its motivation in the foreseeable impact that an accurate, non-invasive and easy-to-use instrument for hemodynamic condition assessment could introduce on the diagnosis and follow-up of these diseases. It aims at developing and testing of a microcontroller based signal monitoring device for cardiovascular studies. The advantages of this system show up in decreasing the associated cost, as well as in increasing its functionality, making the necessary human intervention minimal. The algorithmic component of the project will focus on the main hemodynamic issues currently addressed in literature: separating incident from reflected pulse waves (augmentation index), waveform variability and transfer function Although, additional studies are still required to attain clinical validation, this system seems to be a valid, low cost and easy to use alternative to the highly costly devices in the market. © 2011 IEEE.

2011

Visible and Infrared Optical Probes for Hemodynamic Parameters Assessment

Authors
Pereira, T; Oliveira, T; Cabeleira, M; Almeida, V; Borges, E; Cardoso, J; Correia, C; Pereira, HC;

Publication
2011 IEEE SENSORS

Abstract
Four optical probes were developed to measure the arterial distension waveform generated by the ventricular contraction and assess clinically relevant information. The pressure wave propagates through the arterial tree and can be measured in the peripheral arteries. The probes make use of two distinct photo-detectors: planar and avalanche photodiodes. Independently, two different light sources were tested: visible and infrared light. Performance of the probes was evaluated in a test setup that simulates the fatty deposits commonly seen in the obese, between skin and the artery. The probes show good overall performance in the test setup with less than 8% root mean square error (RMSE). However, the probes lit with IR sources show better results for the more extreme cases, with a better resolution in the waveform, higher definition of notable points and higher SNR when compared to the visible source signals. In vivo, the IR probes allow easier waveform detection, even more relevant with the increasing of the deposit structures.

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