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Abstract
Ensuring the reproducibility of computational scientific experiments is crucial for advancing research and fostering scientific integrity. However, achieving reproducibility poses significant challenges, particularly in the absence of appropriate software tools to help. This paper addresses this issue by comparing existing tools designed to assist researchers across various fields in achieving reproducibility in their work. We were able to successfully run eight tools and execute them to reproduce three existing experiments from different domains. Our findings show the critical role of technical choices in shaping the capabilities of these tools for reproducibility efforts. By evaluating these tools for replicating experiments, we contribute insights into the current landscape of reproducibility support in scientific research. Our analysis offers guidance for researchers seeking appropriate tools to enhance the reproducibility of their experiments, highlighting the importance of informed technical decisions in facilitating reproducibility across diverse domains.

Abstract
Palaeoclimate time series, reflecting the state of Earth's climate in the distant past, occasionally display very large and rapid shifts showing abrupt climate variability. The identification and characterisation of these abrupt transitions in palaeoclimate records is of particular interest as this allows for understanding of millennial climate variability and the identification of potential tipping points in the context of current climate change. Methods that are able to characterise these events in an objective and automatic way, in a single time series, or across two proxy records are therefore of particular interest. In our study the matrix profile approach is used to describe Dansgaard-Oeschger (DO) events, abrupt warmings detected in the Greenland ice core, and Northern Hemisphere marine and continental records. The results indicate that canonical events DO-19 and DO-20, occurring at around 72 and 76 ka, are the most similar events over the past 110 000 years. These transitions are characterised by matching transitions corresponding to events DO-1, DO-8, and DO-12. They are abrupt, resulting in a rapid shift to warmer conditions, followed by a gradual return to cold conditions. The joint analysis of the delta 18O and Ca2+ time series indicates that the transition corresponding to the DO-19 event is the most similar event across the two time series.

Abstract
The Czech Republic is home to the Hranice Abyss, the world's deepest natural underwater cave, a site extensively explored by a dedicated team of divers from a speleology group. Over the years, numerous studies have been conducted to unravel the cave's mysteries, delving into fields such as biology, hydrogeology, and geology. Mapping a cave of such vast dimensions and staggering depth poses formidable challenges, making the task hazardous, demanding, and timeintensive for a limited team of divers. In July 2022, the UNEXUP project was invited to explore and map the cave with its robot (UX1-neo), which contains many acoustic and optical sensors, used for navigation, localization, and mapping. Its unique control and dynamics allow the robot to successfully navigate through caves and flooded mines. This paper delves into the specifics of the six days of mission dives, offering insights into the mapping process, and presenting some of the results obtained from the entire cave.

Abstract
Objectives Space, an extreme environment, poses significant challenges to human physiology, including adverse effects on oral health (e.g., increase of periodontitis prevalence, caries, tooth sensitivity). This study investigates the differences in oral health routines and oral manifestations among analog astronauts during their daily routines and simulated space missions conducted on Earth. Materials and methods This research focused on scientist-astronaut candidates of the International Institute for Astronautical Sciences (IIAS) and analog astronauts from other institutions. The study used a cross-sectional methodology with a descriptive component. A total of 16 participants, comprising individuals aged between 21 and 55 years, were invited to complete an online questionnaire. A comparison was made between the subjects' oral hygiene practices in everyday life (designated as Earth in this research) and their oral hygiene routines during their space analog missions. Results (i) Toothbrushing duration was mostly 1-3 minutes (n = 13; 81.30% on Earth; n = 11; 68.80% on a mission); (ii) time spent was the greatest difficulty in maintaining oral hygiene routine on a mission (n = 9; 53,6%); (iii) There were more experienced oral symptoms on Earth (n = 12; 75%) than on mission (n = 7; 43.80%); (iv) The most frequent frequency of oral check-ups was > 12 months (n = 6; 37,5%); (v) Oral health materials were scarce on the mission (n = 9; 56.30%); (vi) For the majority, personal oral hygiene was classified as good (n = 9; 56.30% on Earth; n = 7; 43.80% on the mission). Conclusion and Clinical relevance This research contributes to increasing knowledge of oral hygiene measures in extreme environments, but further research is needed as this topic remains relatively understudied. This study represents an initial contribution to oral health in analog space missions, aiming to propose guidelines for future missions, including deep space missions and expeditions to extreme environments.