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Publications

2026

Applied Dynamic System Theory for Coordination Assessment of Whole-Body Center of Mass During Different Countermovements

Authors
Rodrigues, C; Correia, MV; Abrantes, JMCS; Rodrigues, MAB; Nadal, J;

Publication
SENSORS

Abstract
This study applies phase plane analysis of medio-lateral, anteroposterior, and vertical directions for the coordination assessment of whole-body (WB) center of mass (COM) movement during the impulse phase of a standard maximum vertical jump (MVJ) with long, short, and no countermovement (CM). A video system and force platform were used, with the amplitudes of WB COM excursion obtained from image-based motion capture at each anatomical direction, and the 2D and 3D mean radial distance were compared under long, short, and no CM conditions. The estimate of the population mean length was used as a measure of distribution concentration, and the Rayleigh statistical test for circular data was applied with the sample distribution critical value. Watson's U2 goodness-of-fit test for the von Mises distribution was used with the mean direction and concentration factor. The applied metrics led to the detection of shared and specific features in the global and phase plane analysis of WB COM movement coordination in the medio-lateral, anteroposterior, and vertical directions during long, short, and no CM conditions in relation to MVJ performance assessed from ground reaction force (GRF) through the force platform. Thus, long, short, and no CM impulses share lower amplitudes of WB COM excursion in the medio-lateral direction and mean radial distance to its mean, whereas the anteroposterior and vertical excursion of WB COM, along with the 2D transversal and 3D spatial length of the WB COM path, present as potential predictors of MVJ performance, with distinct behavior in long CM compared to short and no CM. Additionally, the applied workflow on generalized phase plane analysis led to the detection, through complementary metrics, of the anatomical WB COM movement directions with higher coordination based on phase concentration tests at 5% significance, in line with MVJ performance under different CM conditions.

2026

RIoT Digital Twin: Modeling, Deployment, and Optimization of Reconfigurable IoT System With OpticalRadio Wireless Integration

Authors
Abdellatif, AA; Silva, S; Baltazar, E; Oliveira, B; Qiu, SH; Bocus, MJ; Eder, K; Piechocki, RJ; Almeida, NT; Fontes, H;

Publication
IEEE OPEN JOURNAL OF THE COMMUNICATIONS SOCIETY

Abstract
This paper proposes an optimized Reconfigurable Internet of Things (RIoT) framework that integrates optical and radio wireless technologies with a focus on energy efficiency, scalability, and adaptability. To address the inherent complexity of hybrid optical-radio environments, a high-fidelity Digital Twin (DT) is developed within the Network Simulator 3 (NS-3) platform. The DT models deploy subsystems of the RIoT architecture, including Radio Frequency (RF) communication, Optical Wireless Communication (OWC), and energy harvesting and consumption mechanisms that enable autonomous operation. Real-time energy and power measurements from target hardware platforms are also incorporated to ensure accurate representation of physical behavior and enable runtime analysis and optimization. Building on this foundation, a proactive cross-layer optimization strategy is devised to balance energy efficiency and quality of service (QoS). The strategy dynamically reconfigures RIoT nodes by adapting transmission rates, wake/sleep scheduling, and access technology selection. Results demonstrate that the proposed framework, combining digital twin technology, hybrid optical-radio integration, and data-driven energy modeling, substantially enhances the performance, resilience, and sustainability of 6G IoT networks.

2026

Understanding the Progression of Chronic Kidney Disease in Cats: From Pathophysiology to Emerging Biomarkers

Authors
Rosa, S; Silvestre Ferreira, AC; Martins, R; Queiroga, FP;

Publication
VETERINARY SCIENCES

Abstract
Feline chronic kidney disease is a leading cause of mortality in geriatric cats, characterized by a progressive and irreversible loss of renal function. Despite its high prevalence, early diagnosis remains challenging due to nephron compensatory mechanisms and the limited sensitivity of traditional biomarkers, creating a diagnostic gap that necessitates the exploration of novel biomarkers for earlier detection. This review examines the complex pathophysiology of the disease, including renin-angiotensin-aldosterone system activation, tubulointerstitial fibrosis, and mineral metabolism disturbances. By analyzing recent scientific literature, this work evaluates current diagnostic landscape and clinical relevance of emerging biomarkers. Evidence indicates that symmetric dimethylarginine and fibroblast growth factor-23 improve detection of early metabolic and filtration changes, while urinary biomarkers like cystatin B and retinol-binding protein provide specific insights into tubular injury. Bridging the diagnostic gap requires a transition from a reactive, azotemia-based framework to a multi-parametric diagnostic approach that integrates novel biomarkers with serial clinical and laboratory monitoring. Although financial constraints and limited availability restrict widespread clinical implementation, incorporating these advances is essential for earlier prognostic stratification and timely therapeutic decision-making. This integrated strategy has the potential to slow disease progression and improve survival and quality of life in cats with chronic kidney disease.

2026

On Quantitative Solution Iteration in QAlloy

Authors
Silva, P; Macedo, N; Oliveira, JN;

Publication
RIGOROUS STATE-BASED METHODS, ABZ 2025

Abstract
A key feature of model finding techniques allows users to enumerate and explore alternative solutions. However, it is challenging to guarantee that the generated instances are relevant to the user, representing effectively different scenarios. This challenge is exacerbated in quantitative modelling, where one must consider both the qualitative, structural part of a model, and the quantitative data on top of it. This results in a search space of possibly infinite candidate solutions, often infinitesimally similar to one another. Thus, research on instance enumeration in qualitative model finding is not directly applicable to the quantitative context, which requires more sophisticated methods to navigate the solution space effectively. The main goal of this paper is to explore a generic approach for navigating quantitative solution spaces and showcase different iteration operations, aiming to generate instances that differ considerably from those previously seen and promote a larger coverage of the search space. Such operations are implemented in QAlloy - a quantitative extension to Alloy - on top of Max-SMT solvers, and are evaluated against several examples ranging, in particular, over the integer and fuzzy domains.

2026

Disentanglement and Assessment of Shortcuts in Ophthalmological Retinal Imaging Exams

Authors
Fernandes, L; Goncalves, T; Matos, J; Nakayama, L; Cardoso, JS;

Publication
FAIRNESS OF AI IN MEDICAL IMAGING, FAIMI 2025

Abstract
Diabetic retinopathy (DR) is a leading cause of vision loss in working-age adults. While screening reduces the risk of blindness, traditional imaging is often costly and inaccessible. Artificial intelligence (AI) algorithms present a scalable diagnostic solution, but concerns regarding fairness and generalization persist. This work evaluates the fairness and performance of image-trained models in DR prediction, as well as the impact of disentanglement as a bias mitigation technique, using the diverse mBRSET fundus dataset. Three models, ConvNeXt V2, DINOv2, and Swin V2, were trained on macula images to predict DR and sensitive attributes (SAs) (e.g., age and gender/sex). Fairness was assessed between subgroups of SAs, and disentanglement was applied to reduce bias. All models achieved high DR prediction performance in diagnosing (up to 94% AUROC) and could reasonably predict age and gender/sex (91% and 77% AUROC, respectively). Fairness assessment suggests disparities, such as a 10% AUROC gap between age groups in DINOv2. Disentangling SAs from DR prediction had varying results, depending on the model selected. Disentanglement improved DINOv2 performance (2% AUROC gain), but led to performance drops in ConvNeXt V2 and Swin V2 (7% and 3%, respectively). These findings highlight the complexity of disentangling fine-grained features in fundus imaging and emphasize the importance of fairness in medical imaging AI to ensure equitable and reliable healthcare solutions.

2026

Point-of-Care Veterinary Diagnostics Using Vis-NIR Spectroscopy: Current Opportunities and Future Directions

Authors
Rosa, S; Silvestre-Ferreira, AC; Martins, R; Queiroga, FL;

Publication
ANIMALS

Abstract
Visible-Near-Infrared (Vis-NIR) spectroscopy, spanning approximately 400 to 2500 nm, is an innovative technology with growing relevance for diagnostics performed at the point of care (POC). This review explores the potential of Vis-NIR in veterinary medicine, highlighting its advantages over complex techniques like Raman and Fourier transform infrared spectroscopy (FTIR) by being rapid, non-invasive, reagent-free, and compatible with miniaturized, portable devices. The methodology involves directing a broadband light source, often using LEDs, toward the sample (e.g., blood, urine, faeces), collecting spectral information related to molecular vibrations, which is then analyzed using chemometric methods. Successful veterinary applications include hemogram analysis in dogs, cats, and Atlantic salmon, and quantifying blood in ovine faeces for parasite detection. Key limitations include spectral interference from strong absorbers like water and hemoglobin, and the limited penetration depth of light. However, combining Vis-NIR with Self-Learning Artificial Intelligence (SLAI) is shown to isolate and mitigate these multi-scale interferences. Vis-NIR spectroscopy serves as an important complement to centralized laboratory testing, holding significant potential to accelerate clinical decisions, minimize stress on animals during assessment, and improve diagnostic capabilities for both human and animal health, aligning with the One Health concept.

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