Abstract
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Abstract
Bipolar Disorder (BD) is a chronic and severe psychiatric illness presenting with mood alterations, including manic, hypomanic, and depressive episodes. Due to the high clinical heterogeneity and lack of biological validation, both treatment and diagnosis of BD remain problematic and challenging. In this context, this paper proposes a novel intelligent system applied to the diagnosis of BD. First, each patient’s single nucleotide polymorphism (SNP) data is represented by QR codes, which reduces the high dimensionality of the problem and homogenizes the data representation. For the initial tests of the system, the Wellcome Trust Case Control Consortium (WTCCC) dataset was used. The preliminary results are encouraging, with an AUC value of 0.82 and an accuracy of 82%, correctly classifying all cases and most controls. This approach reduces the dimensionality of large amounts of data and can help improve diagnosis and deliver the right treatment to the patient. Furthermore, the architecture of the system is versatile and could be adapted and used to diagnose other diseases where there is also high dimensionality. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.

Abstract
In this work, we assess the impact of self-supervised learning (SSL) approaches on the detection of gastritis atrophy (GA) and intestinal metaplasia (IM) conditions. GA and IM are precancerous gastric lesions. Detecting these lesions is crucial to intervene early and prevent their progression to cancer. A set of experiments is conducted over the Chengdu dataset, by considering different amounts of annotated data in the training phase. Our results reveal that, when all available data is used for training, SSL approaches achieve a classification accuracy on par with a supervised learning baseline, (81.52% vs 81.76%). Interestingly, we observe that in low-data regimes (here represented as retaining only 12.5% of annotated data for training), the SSL model guarantees an accuracy gain with respect to the supervised learning baseline of approximately 1.5% (73.00% vs 71.52%). This observation hints at the potential of SSL models in leveraging unlabeled data, thus showcasing more robust performance improvements and generalization. Experimental results also show that SSL performance is significantly dependent on the specific data augmentation techniques and parameters adopted for contrastive learning, thus advocating for further investigations into the definition of optimal data augmentation frameworks specifically tailored for gastric lesion detection applications.

Abstract
Retailers face increasing competitive pressure to determine how best to deliver products purchased online to the end customer. Grocery retailers often require attended home delivery where the customer must be present to receive the delivery. For attended home delivery to function, the retailer and customer must agree on a delivery time slot that works for both parties. Using online data from a grocery retailer, we observe customer preferences for three delivery service attributes associated with each time slot: speed, precision, and timing. We define speed as the expected time between the placement of an order and its delivery, precision as the duration of the offered time slot, and timing as the availability of choices across times of the day and days of the week. We show that customers not only value speed as an attribute of delivery service but that precision and timing are also key drivers of the customer's time slot selection process. We also observe substantial customer heterogeneity in the willingness of customers to pay for time slots. Customers that differ in their loyalty to the retailer, basket value, basket size, and basket composition exhibit distinct differences in their willingness to pay. We show that retailers with the capability to tailor their time slot offerings to specific customer segments have the potential to generate approximately 9% more shipping revenue than those who cannot. Our findings inform practitioners seeking to design competitive fulfillment strategies and academics customer behavior in the attended home context.

Abstract
This paper introduces the Kabsch Marker Estimation Algorithm (KMEA), a new, robust multi-marker localization method designed for Autonomous Mobile Robots (AMRs) within Industry 4.0 (I4.0) settings. By integrating the Kabsch Algorithm, our approach significantly enhances localization robustness by aligning detected fiducial markers with their known positions. Unlike conventional methods that rely on a limited subset of visible markers, the KMEA uses all available markers, without requiring the camera's extrinsic parameters, thereby improving robustness. The algorithm was validated in an I4.0 automated warehouse mockup, with a four-stage methodology compared to a previously established marker estimation algorithm for reference. On the one hand, the results have demonstrated the KMEA's similar performance in standard controlled scenarios, with millimetric precision across a set of error metrics and a mean relative error (MRE) of less than 1%. On the other hand, KMEA, when faced with challenging test scenarios with outliers, showed significantly superior performance compared to the baseline algorithm, where it maintained a millimetric to centimetric scale in error metrics, whereas the other suffered extreme degradation. This was emphasized by the average reduced results of error metrics from 86.9% to 92% in Parts III and IV of the test methodology, respectively. These results were achieved using low-cost hardware, indicating the possibility of even greater accuracy with advanced equipment. The paper details the algorithm's development, theoretical framework, comparative advantages over existing methods, discusses the test results, and concludes with comments regarding its potential for industrial and commercial applications by its scalability and reliability.

Abstract
In today's knowledge-driven economy, collaboration among stakeholders is essential for the framing of innovative trends, with knowledge-intensive business services (KIBS) playing a core role in addressing market demand. Users' involvement in shaping products and services has been considered in innovation ecosystem frameworks. Fewer risks in service/product development, and more sustainability and market acceptance, are a few of the benefits arising from including the user community (UC) in innovation partnerships. However, the need for resources, absorptive capacity and tacit knowledge, among other capabilities, is often a reason for overlooking this important contributor. KIBS possess a vast knowledge base, cater to digital tools, and mediate and propel innovation with different partners, benefiting from exclusive cognitive proximity to remix extant knowledge with emergent information from communities into new products and services. The aim of this study is to assess and quantify the effect of the collaboration with UC through three active forms of collaboration (co-creation, mass customization, and personalization) on different innovation types developed in KIBS. The significance of the user community was proven across all innovation types. Robustness analysis confirmed the results for both P-KIBS and T-KIBS. P-KIBS may be better suited to co-creation policies for product and service innovation, personalization of processes, and organizational and marketing innovations. T-KIBS can focus on mass customization, ensuring good innovation success. Additionally, co-creation with user community is best for product innovation.