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Sobre

Sobre

Bruno M. P. M. Oliveira é professor auxiliar na Universidade do Porto (Portugal) e investigador do LIAAD, INESC TEC. É licenciado em Astronomia, Mestre em Matemática Aplicada, Doutor em Matemática Aplicada e fez a Agregação em Nutrição Clínica - Ciências Básicas.
Investiga em diversas áreas da Matemática que incluem Sistemas Dinâmicos, Teoria de Jogos e Estatística.
Tem particular interesse pelas aplicações em Ciências da Nutrição e Alimentação (em especial em Nutrição Clínica e Ciências do Consumo Alimentar e Nutrição), Imunologia (em particular modelação de células T e Tregs), Epidemiologia e Economia (em particular em competição de Cournot e em mercados de emparelhamento aleatório).
Participou em projectos de investigação financiados pela UE e pela FCT Portuguesa, abrangendo as Ciências da Nutrição e Alimentação e Matemática.

Tópicos
de interesse
Detalhes

Detalhes

  • Nome

    Bruno Mendes Oliveira
  • Cargo

    Investigador Sénior
  • Desde

    01 abril 2012
001
Publicações

2025

Evaluating the Therapeutic Potential of Exercise in Hypoxia and Low-Carbohydrate, High-Fat Diet in Managing Hypertension in Elderly Type 2 Diabetes Patients: A Novel Intervention Approach

Autores
Kindlovits, R; Sousa, AC; Viana, JL; Milheiro, J; Oliveira, BMPM; Marques, F; Santos, A; Teixeira, VH;

Publicação
NUTRIENTS

Abstract
Background/Objectives: Type 2 diabetes mellitus (T2DM) is a chronic condition marked by hyperglycemia, which can affect metabolic, vascular, and hematological parameters. A low-carbohydrate, high-fat (LCHF) diet has been shown to improve glycemic control and blood pressure regulation. Exercise in hypoxia (EH) enhances insulin sensitivity, erythropoiesis, and angiogenesis. The combination of LCHF and EH may offer a promising strategy for managing T2DM and hypertension (HTN), although evidence remains limited. This study aimed to assess the effects of an eight-week normobaric EH intervention at 3000 m simulated altitude combined with an LCHF diet on hematological and lipid profiles, inflammation, and blood pressure in older patients with T2DM and HTN. Methods: Forty-two diabetic patients with HTN were randomly assigned to three groups: (1) control group (control diet + exercise in normoxia), (2) EH group (control diet + EH), and (3) intervention group (EH+LCHF) Baseline and eight-week measurements included systolic, diastolic, and mean blood pressure (SBP, DBP, MAP), hematological and lipid profiles, and inflammation biomarkers. Results: Blood pressure decreased after the intervention (p < 0.001), with no significant differences between groups (SBP: p = 0.151; DBP: p = 0.124; MAP: p = 0.18). No differences were observed in lipid profile or C-reactive protein levels (p > 0.05). Mean corpuscular hemoglobin (MCH) increased in the EH group (p = 0.027), while it decreased in the EH+LCHF group (p = 0.046). Conclusions: Adding hypoxia or restricting carbohydrates did not provide additional benefits on blood pressure in T2DM patients with HTN. Further elucidation of the mechanisms underlying hematological adaptations is imperative.

2025

Evaluating the Therapeutic Potential of Exercise in Hypoxia and Low-Carbohydrate High-Fat Diet in Managing Hypertension in Elderly Type 2 Diabetes Patients: A Novel Intervention Approach

Autores
Kindlovits, R; Sousa, AC; Viana, JL; Milheiro, J; Oliveira, BMPM; Marques, F; Santos, A; Teixeira, VH;

Publicação

Abstract
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by hyperglycemia, which could alter metabolic, vascular and hematological parameters. A low-carbohydrate, high-fat diet (LCHF) diet benefits glycemic and blood pressure control. In turn, exercise in hypoxia (EH) is known to improve insulin sensitivity, erythropoiesis and angiogenesis. LCHF combined with EH seem to be a potential therapeutic strategy for T2DM and hypertension (HTN), but evidence is still scarce. The aim of this study was to evaluate the effects of eight weeks of EH combined with a LCHF on hematological and lipid profiles, inflammation and blood pressure in older patients with T2DM and coexistent HTN. Diabetic patients with HTN (n=42) were randomly assigned to a (1) control group: control diet (high-carbohydrate and low-fat diet) + exercise in normoxia; (2) EH group: control diet + EH; (3) intervention group: LCHF + EH. Baseline and eight-week measurements included systolic, diastolic, and mean blood pressure (SBP, DBP, MAP, respectively), and hematological and lipid profiles and inflammation biomarkers. Blood pressure decreased after interventions (p&amp;lt;0.001), with no differences among groups (SBP: p=0.151; DBP: p=0.124 and MAP: p=0.18). There were no differences in lipid profile and C-reactive protein (p&amp;gt;0.05). Mean corpuscular hemoglobin (MCH) increased in the EH group (p=0.027), while MCH concentration decreased in the EH+LCHF group (p=0.046). In conclusion, there is no additional benefit in adding hypoxia to exercise or restricting carbohydrates, on blood pressure in patients with T2DM and coexisting HTN. Further elucidation of the mechanisms underlying hematological adaptations is imperative. Trial registration number: NCT05094505.

2024

Assessment of Intuitive Eating and Mindful Eating among Higher Education Students: A Systematic Review

Autores
Rezende, F; Oliveira, BMPM; Poínhos, R;

Publicação
HEALTHCARE

Abstract
Background: The role of mindful eating (ME) and intuitive eating (IE) in improving eating behavior, diet quality, and health is an area of increasing interest. Objective: The objective of this review was to identify the instruments used to assess ME and IE among higher education students and outcomes related to these dimensions. Methods: This review was carried out according to the PRISMA statement, through systematic searches in PubMed, Web of Science, PsycInfo, and Scopus. The inclusion criteria selected for higher education students, levels of ME and/or IE reported, and observational and clinical studies. The exclusion criteria selected against reviews, qualitative studies, and case studies. Quality was assessed using the Academy of Nutrition and Dietetics Quality Criteria Checklist. Results: A total of 516 initial records were identified, from which 75 were included. Cross-sectional studies were the most common research design (86.7%). Most studies were conducted with samples that were predominantly female (90.7%), White (76.0%), aged 18 to 22 years (88.4%), with BMI < 25 kg/m(2) (83.0%), and in the United States (61.3%). The Intuitive Eating Scale (IES), the Mindful Eating Questionnaire (MEQ), and their different versions were the most used instruments. The outcomes most studies included were eating behavior and disorders (77.3%), anthropometric assessments (47.8%), mental health (42.0%), and body image (40.6%). Regarding the quality of studies, 34.7% of studies were assigned a positive, 1.3% a negative, and 64.0% a neutral rate. Conclusions: IES and MEQ were the most used instruments. RCT and cohort studies are scarce, and future research with a higher level of quality is needed, especially on the topics of food consumption, diet quality, and biochemical markers.

2024

Eight Weeks of Intermittent Exercise in Hypoxia, with or without a Low-Carbohydrate Diet, Improves Bone Mass and Functional and Physiological Capacity in Older Adults with Type 2 Diabetes

Autores
Kindlovits, R; Sousa, AC; Viana, JL; Milheiro, J; Oliveira, BMPM; Marques, F; Santos, A; Teixeira, VH;

Publicação
NUTRIENTS

Abstract
In an increasingly aging and overweight population, osteoporosis and type 2 diabetes (T2DM) are major public health concerns. T2DM patients experience prejudicial effects on their bone health, affecting their physical capacity. Exercise in hypoxia (EH) and a low-carbohydrate diet (LCD) have been suggested for therapeutic benefits in T2DM, improving bone mineral content (BMC) and glycemic control. This study investigated the effects of EH combined with an LCD on body composition and functional and physiologic capacity in T2DM patients. Older T2DM patients (n = 42) were randomly assigned to the following groups: (1) control group: control diet + exercise in normoxia; (2) EH group: control diet + EH; (3) intervention group: LCD + EH. Cardiopulmonary tests (BRUCE protocol), body composition (DEXA), and functional capacity (6MWT, handgrip strength) were evaluated. Body mass index (kg/m(2)) and body fat (%) decreased in all groups (p < 0.001). BMC (kg) increased in all groups (p < 0.001) and was significantly higher in the EH and EH + LCD groups (p < 0.001). VO2peak improved in all groups (p < 0.001), but more so in the hypoxia groups (p = 0.019). Functional capacity was increased in all groups (p < 0.001), but more so in the EH group in 6MWT (p = 0.030). EH with and without an LCD is a therapeutic strategy for improving bone mass in T2DM, which is associated with cardiorespiratory and functional improvements.

2024

Risk of Eating Disorders and Social Desirability among Higher Education Students: Comparison of Nutrition Students with Other Courses

Autores
Fernandes, S; Costa, C; Nakamura, IS; Poínhos, R; Oliveira, BMPM;

Publicação
HEALTHCARE

Abstract
The transition to college is a period of higher risk of the development of eating disorders, with nutrition/dietetics students representing a group of particular vulnerability. Hence, it is interesting to assess eating disorders, taking into consideration potential sources of bias, including social desirability. Our aims were to compare the risk of eating disorders between students of nutrition/dietetics and those attending other courses and to study potential social desirability biases. A total of 799 higher education students (81.7% females) aged 18 to 27 years old completed a questionnaire assessing the risk of eating disorders (EAT-26) and social desirability (composite version of the Marlowe-Crowne Social Desirability Scale). The proportion of students with a high risk of eating disorders was higher among females (14.5% vs. 8.2%, p = 0.044). Nutrition/dietetics students did not differ from those attending other courses regarding the risk of eating disorders. The social desirability bias when assessing the risk of eating disorders was overall low (EAT-26 total score: r = -0.080, p = 0.024). Social desirability correlated negatively with the Diet (r = -0.129, p < 0.001) and Bulimia and food preoccupation subscales (r = -0.180, p < 0.001) and positively with Oral self-control (r = 0.139, p < 0.001).

Teses
supervisionadas

2022

Determinação das necessidades  energéticas de doentes críticos  ventilados com COVID-19

Autor
Sara Vieira Serdoura

Instituição
UP-FCNAUP

2022

Prevalência de Perturbações do Comportamento Alimentar na adolescência: uma Revisão Sistemática

Autor
Cátia Filipa Coelho Ramalho

Instituição
UP-FCNAUP

2022

Applications of Game Theory and Dynamical Systems to Biology and Economy

Autor
Atefeh Afsar

Instituição
UP-FCNAUP

2022

Impacto do Índice de Massa Corporal no Diagnóstico na Doença de Crohn

Autor
Ana Filipa Gonçalves Dias

Instituição
UP-FCNAUP

2022

Comportamento alimentar e risco de perturbações do comportamento alimentar em estudantes de ensino superior

Autor
Carolina Noronha Ribeiro da Costa

Instituição
UP-FCNAUP