Abstract
System of systems involves several secondary systems working together with its creation gathering the knowledge of several distinct disciplines and teams, each one with their own background and methods, leading to a difficult communication between them. SysML, a language originated from UML, enables that communication, without background interference, with the use of a rich notation for systems design. This paper analyzes its use through the experience gained in the design of a chemical system with SysML.

Abstract
We present a new method for generating input features for musical audio beat tracking systems. To emphasise periodic structure we derive a weighted linear combination of sub-band onset detection functions driven a measure of sub-band beat strength. Results demonstrate improved performance over existing state of the art models, in particular for musical excerpts with a steady tempo. ©2009 IEEE.

Abstract
In this paper we present a model for beat-synchronous analysis of musical audio signals. Introducing a real-time beat tracking model with performance comparable to offline techniques, we discuss its application to the analysis of musical performances segmented by beat. We discuss the various design choices for beat-synchronous analysis and their implications for real-time implementations before presenting some beat-synchronous harmonic analysis examples. We make available our beat tracker and beat-synchronous analysis techniques as externals for Max/MSP.

Abstract
Three-dimensional (3D) objects reconstruction using just bi-dimensional (2D) images has been a major research topic in Computer Vision. However, it is still a hard problem to address, when automation, speed and precision are required and/or the objects have complex shapes or image properties. In this paper, we compare two Active Computer Vision methods frequently used for the 3D reconstruction of objects from image sequences, acquired with a single off-the-shelf CCD camera: Structure From Motion (SFM) and Generalized Voxel Coloring (GVC). SFM recovers the 3D shape of an object based on the relative motion involved, while VC is a volumetric method that uses photo-consistency measures to build the required 3D model. Both methods considered do not impose any kind of restrictions on the relative motion involved. © Springer Science+Business Media B.V. 2009.

Abstract
Three-dimensional (3D) objects reconstruction using just bi-dimensional (2D) images has been a major research topic in Computer Vision. However, it is still a hard problem to address, when automation, speed and precision are required and/or the objects have complex shapes or image properties. In this paper, we compare two Active Computer Vision methods frequently used for the 3D reconstruction of objects from image sequences, acquired with a single off-the-shelf CCD camera: Structure From Motion (SFM) and Generalized Voxel Coloring (GVC). SFM recovers the 3D shape of an object based on the relative motion involved, while VC is a volumetric method that uses photo-consistency measures to build the required 3D model. Both methods considered do not impose any kind of restrictions on the relative motion involved.

Abstract
Diabetic retinopathy (DR) is the leading cause of blindness in adults. In diabetes, there is activation of microglial cells and a concomitant release of inflammatory mediators. However, it remains unclear how diabetes triggers an inflammatory response in the retina. Activation of P2 purinergic receptors by adenosine triphosphate (ATP) may contribute to the inflammatory response in the retina, insofar as it has been shown to be associated with microglial activation and cytokine release. In this work, we evaluated how high glucose, used as a model of hyperglycemia, considered the main factor in the development of DR, affects the extracellular levels of ATP in retinal cell cultures. We found that basal extracellular ATP levels were not affected by high glucose or mannitol, but the extracellular elevation of ATP, after a depolarizing stimulus, was significantly higher in retinal cells cultured in high glucose compared with control or mannitol-treated cells. The increase in the extracellular ATP was prevented by application of botulinum neurotoxin A or by removal of extracellular calcium. In addition, degradation of exogenously added ATP was significantly lower in high-glucose-treated cells. It was also observed that, in retinal cells cultured under high-glucose conditions, the changes in the intracellular calcium concentrations were greater than those in control or mannitol-treated cells. In conclusion, in this work we have shown that high glucose alters the purinergic signaling system in the retina, by increasing the exocytotic release of ATP and decreasing its extracellular degradation. The resulting high levels of extracellular ATP may lead to inflammation involved in the pathogenesis of DR. (C) 2008 Wiley-Liss, Inc.