Abstract
Dermoscopic images allow the detailed examination of subsurface characteristics of the skin, which led to creating several substantial databases of diverse skin lesions. However, the dermoscope is not an easily accessible tool in some regions. A less expensive alternative could be acquiring medium resolution clinical macroscopic images of skin lesions. However, the limited volume of macroscopic images available, especially mobile-acquired, hinders developing a clinical mobile-based deep learning approach. In this work, we present a technique to efficiently utilize the sizable number of dermoscopic images to improve the segmentation capacity of macroscopic skin lesion images. A Cycle-Consistent Adversarial Network is used to translate the image between the two distinct domains created by the different image acquisition devices. A visual inspection was performed on several databases for qualitative evaluation of the results, based on the disappearance and appearance of intrinsic dermoscopic and macroscopic features. Moreover, the Frechet Inception Distance was used as a quantitative metric. The quantitative segmentation results are demonstrated on the available macroscopic segmentation databases, SMARTSKINS and Dermofit Image Library, yielding test set thresholded Jaccard Index of 85.13% and 74.30%. These results establish a new state-of-the-art performance in the SMARTSKINS database.

Abstract
The scarcity of balanced and annotated datasets has been a recurring problem in medical image analysis. Several researchers have tried to fill this gap employing dataset synthesis with adversarial networks (GANs). Breast magnetic resonance imaging (MRI) provides complex, texture-rich medical images, with the same annotation shortage issues, for which, to the best of our knowledge, no previous work tried synthesizing data. Within this context, our work addresses the problem of synthesizing breast MRI images from corresponding annotations and evaluate the impact of this data augmentation strategy on a semantic segmentation task. We explored variations of image-to-image translation using conditional GANs, namely fitting the generator's architecture with residual blocks and experimenting with cycle consistency approaches. We studied the impact of these changes on visual verisimilarity and how an U-Net segmentation model is affected by the usage of synthetic data. We achieved sufficiently realistic-looking breast MRI images and maintained a stable segmentation score even when completely replacing the dataset with the synthetic set. Our results were promising, especially when concerning to Pix2PixHD and Residual CycleGAN architectures.

Abstract
Industry 4.0 is changing the manufacturing paradigms across industries. However, many repetitive processes still rely heavily on human workers, as in the case of the automotive industry, where the final quality inspection of assembled vehicles is still performed using a paper-based conformity list. We instead propose a hybrid solution where a deep learning-based hierarchical autonomous detection system identifies the non-conforming parts and informs the operator via a wearable device, trained exclusively with simulated data. This scalable and cost-effective system achieved a 65.7% accuracy score, which, considering the experimental nature of this work, further confirms the potential of this approach.

Abstract
With the increasing adoption of teledermatology, there is a need to improve the automatic organization of medical records, being dermatological image modality a key filter in this process. Although there has been considerable effort in the classification of medical imaging modalities, this has not been in the field of dermatology. Moreover, as various devices are used in teledermatological consultations, image acquisition conditions may differ. In this work, two models (VGG-16 and MobileNetV2) were used to classify dermatological images from the Portuguese National Health System according to their modality. Afterwards, four incremental learning strategies were applied to these models, namely naive, elastic weight consolidation, averaged gradient episodic memory, and experience replay, enabling their adaptation to new conditions while preserving previously acquired knowledge. The evaluation considered catastrophic forgetting, accuracy, and computational cost. The MobileNetV2 trained with the experience replay strategy, with 500 images in memory, achieved a global accuracy of 86.04% with only 0.0344 of forgetting, which is 6.98% less than the second-best strategy. Regarding efficiency, this strategy took 56 s per epoch longer than the baseline and required, on average, 4554 megabytes of RAM during training. Promising results were achieved, proving the effectiveness of the proposed approach.

Abstract
Considerable amounts of data are required for a deep learning model to generalize to unseen cases successfully. Furthermore, such data is often manually labeled, making its annotation process costly and time-consuming. We propose using unlabeled real-world data in conjunction with automatically labeled synthetic data, obtained from simulators, to surpass the increasing need for annotated data. By obtaining real counterparts of simulated samples using CycleGAN and subsequently performing fine-tuning with such samples, we manage to improve a vehicle part's detection system performance by 2.5%, compared to the baseline exclusively trained on simulated images. We explore adding a semantic consistency loss to CycleGAN by re-utilizing previous work's trained networks to regularize the conversion process. Moreover, the addition of a post-processing step, which we denominate global NMS, highlights our approach's effectiveness by better utilizing our detection model's predictions and ultimately improving the system's performance by 14.7%.

Abstract
The high incidence of cervical cancer in women has prompted the research of automatic screening methods. This work focuses on two of the steps present in such systems, more precisely, the identification of cervical lesions and their respective classification. The development of automatic methods for these tasks is associated with some shortcomings, such as acquiring sufficient and representative clinical data. These limitations are addressed through a hybrid pipeline based on a deep learning model (RetinaNet) for the detection of abnormal regions, combined with random forest and SVM classifiers for their categorization, and complemented by the use of domain knowledge in its design. Additionally, the nuclei in each detected region are segmented, providing a set of nuclei-specific features whose impact on the classification result is also studied. Each module is individually assessed in addition to the complete system, with the latter achieving a precision, recall and F1 score of 0.04, 0.20 and 0.07, respectively. Despite the low precision, the system demonstrates potential as an analysis support tool with the capability of increasing the overall sensitivity of the human examination process.