Abstract
Importance Mammography screening currently relies on subjective human interpretation. Artificial intelligence (AI) advances could be used to increase mammography screening accuracy by reducing missed cancers and false positives. Objective To evaluate whether AI can overcome human mammography interpretation limitations with a rigorous, unbiased evaluation of machine learning algorithms. Design, Setting, and Participants In this diagnostic accuracy study conducted between September 2016 and November 2017, an international, crowdsourced challenge was hosted to foster AI algorithm development focused on interpreting screening mammography. More than 1100 participants comprising 126 teams from 44 countries participated. Analysis began November 18, 2016. Main Outcomes and Measurements Algorithms used images alone (challenge 1) or combined images, previous examinations (if available), and clinical and demographic risk factor data (challenge 2) and output a score that translated to cancer yes/no within 12 months. Algorithm accuracy for breast cancer detection was evaluated using area under the curve and algorithm specificity compared with radiologists' specificity with radiologists' sensitivity set at 85.9% (United States) and 83.9% (Sweden). An ensemble method aggregating top-performing AI algorithms and radiologists' recall assessment was developed and evaluated. Results Overall, 144 & x202f;231 screening mammograms from 85 & x202f;580 US women (952 cancer positive <= 12 months from screening) were used for algorithm training and validation. A second independent validation cohort included 166 & x202f;578 examinations from 68 & x202f;008 Swedish women (780 cancer positive). The top-performing algorithm achieved an area under the curve of 0.858 (United States) and 0.903 (Sweden) and 66.2% (United States) and 81.2% (Sweden) specificity at the radiologists' sensitivity, lower than community-practice radiologists' specificity of 90.5% (United States) and 98.5% (Sweden). Combining top-performing algorithms and US radiologist assessments resulted in a higher area under the curve of 0.942 and achieved a significantly improved specificity (92.0%) at the same sensitivity. Conclusions and Relevance While no single AI algorithm outperformed radiologists, an ensemble of AI algorithms combined with radiologist assessment in a single-reader screening environment improved overall accuracy. This study underscores the potential of using machine learning methods for enhancing mammography screening interpretation. Question How do deep learning algorithms perform compared with radiologists in screening mammography interpretation? Findings In this diagnostic accuracy study using 144 & x202f;231 screening mammograms from 85 & x202f;580 women from the United States and 166 & x202f;578 screening mammograms from 68 & x202f;008 women from Sweden, no single artificial intelligence algorithm outperformed US community radiologist benchmarks; including clinical data and prior mammograms did not improve artificial intelligence performance. However, combining best-performing artificial intelligence algorithms with single-radiologist assessment demonstrated increased specificity. Meaning Integrating artificial intelligence to mammography interpretation in single-radiologist settings could yield significant performance improvements, with the potential to reduce health care system expenditures and address resource scarcity experienced in population-based screening programs. This diagnostic accuracy study evaluates whether artificial intelligence can overcome human mammography interpretation limits with a rigorous, unbiased evaluation of machine learning algorithms.

Abstract
Video summarization is an important tool considering the amount of data to analyze. Techniques in this area aim to yield synthetic and useful visual abstraction of the videos contents. Hence, in this paper we present a new summarization algorithm, based on image features, which is composed by the following steps: (i) Query video processing using cosine similarity metric and total variation smoothing to identify classes in the query sequence; (ii) With this result, build a labeled training set of frames; (iii) Generate the unlabeled training set composed by samples of the video database; (iv) Training a deep semi-supervised autoencoder; (v) Compute the K-means for each video separately, in the encoder space, with the number of clusters set as a percentage of the video size; (vi) Select key-frames in the K-means clusters to define the summaries. In this methodology, the query video is used to incorporate prior knowledge in the whole process through the obtained labeled data. The step (iii) aims to include unknown patterns useful for the summarization process. We evaluate the methodology using some videos from OPV video database. We compare the performance of our algorithm with the VSum. The results indicate that the pipeline was well succeed in the summarization presenting a F-score value superior to VSum.

Abstract

Abstract
When encountering a dubious diagnostic case, radiologists typically search in public or internal databases for similar cases that would help them in their decision-making process. This search represents a massive burden to their workflow, as it considerably reduces their time to diagnose new cases. It is, therefore, of utter importance to replace this manual intensive search with an automatic content-based image retrieval system. However, general content-based image retrieval systems are often not helpful in the context of medical imaging since they do not consider the fact that relevant information in medical images is typically spatially constricted. In this work, we explore the use of interpretability methods to localize relevant regions of images, leading to more focused feature representations, and, therefore, to improved medical image retrieval. As a proof-of-concept, experiments were conducted using a publicly available Chest X-ray dataset, with results showing that the proposed interpretability-guided image retrieval translates better the similarity measure of an experienced radiologist than state-of-the-art image retrieval methods. Furthermore, it also improves the class-consistency of top retrieved results, and enhances the interpretability of the whole system, by accompanying the retrieval with visual explanations. © Springer Nature Switzerland AG 2020.

Abstract
Fingerprint presentation attack detection (PAD) methods present a stunning performance in current literature. However, the fingerprint PAD generalisation problem is still an open challenge requiring the development of methods able to cope with sophisticated and unseen attacks as our eventual intruders become more capable. This work addresses this problem by applying a regularisation technique based on an adversarial training and representation learning specifically designed to to improve the PAD generalisation capacity of the model to an unseen attack. In the adopted approach, the model jointly learns the representation and the classifier from the data, while explicitly imposing invariance in the high-level representations regarding the type of attacks for a robust PAD. The application of the adversarial training methodology is evaluated in two different scenarios: i) a handcrafted feature extraction method combined with a Multilayer Perceptron (MLP); and ii) an end-to-end solution using a Convolutional Neural Network (CNN). The experimental results demonstrated that the adopted regularisation strategies equipped the neural networks with increased PAD robustness. The adversarial approach particularly improved the CNN models' capacity for attacks detection in the unseen-attack scenario, showing remarkable improved APCER error rates when compared to state-of-the-art methods in similar conditions.

Abstract