Abstract

Abstract

Abstract

Abstract
Heart sounds are difficult to interpret because a) they are composed by several different sounds, all contained in very tight time windows; b) they vary from physiognomy even if the show similar characteristics; c) human ears are not naturally trained to recognize heart sounds. Computer assisted decision systems may help but they require robust signal processing algorithms. In this paper, we use a real life dataset in order to compare the performance of a hidden Markov model and several hidden semi Markov models that used the Poisson, Gaussian, Gamma distributions, as well as a non-parametric probability mass function to model the sojourn time. Using a subject dependent approach, a model that uses the Poisson distribution as an approximation for the sojourn time is shown to outperform all other models. This model was able to recreate the "true" state sequence with a positive predictability per state of 96%. Finally, we used a conditional distribution in order to compute the confidence of our classifications. By using the proposed confidence metric, we were able to identify wrong classifications and boost our system (in average) from an approximate to 83% up to approximate to 90% of positive predictability per sample.

Abstract
In this work, we present a method to extract features from heart sound signals in order to enhance segmentation performance. The approach is data-driven, since the way features are extracted from the recorded signals is adapted to the data itself. The proposed method is based on the extraction of delay vectors, which are modeled with Gaussian mixture model priors, and an information-theoretic dimensionality reduction step which aims to maximize discrimination between delay vectors in different segments of the heart sound signal. We test our approach with heart sounds from the publicly available PhysioNet dataset showing an average F-1 score of 92.6% in detecting S-1 and S-2 sounds.

Abstract
Automatic and simultaneous electrocardiogram (ECG) and phonocardiogram (PCG) segmentation is a good example of current challenges when designing multi-channel decision support systems for healthcare. In this paper, we implemented and tested a Montazeri coupled hidden Markov model (CHMM), where two HMM's cooperate to recreate the "true" state sequence. To evaluate its performance, we tested different settings (two fully connected and two partially connected channels) on a real dataset annotated by an expert. The fully connected model achieved 71% of positive predictability (P+) on the ECG channel and 67% of P+ on the PCG channel. The partially connected model achieved 90% of P+ on the ECG channel and 80% of P+ in the PCG channel. These results validate the potential of our approach for real world multichannel application systems.