2010
Autores
Pedrosa, C; Oliveira, BMPM; Albuquerque, I; Simoes Pereira, C; Vaz de Almeida, MD; Correia, F;
Publicação
DIABETOLOGY & METABOLIC SYNDROME
Abstract
Background: Body fat is related to changes in lipid profile, blood pressure and metabolism of insulin and glucose, known as the metabolic syndrome (MS). The aim of this study was to estimate the prevalence of metabolic syndrome (MS) and its components among overweight and obese Portuguese schoolchildren, and to identify associated clinical and biochemical characteristics. Methods: A total of 82 children (14 overweight and 68 obese; 40 boys and 42 girls) aged 7-9 years, underwent anthropometric measurements. A blood sample was obtained to assess biochemical parameters. Insulin resistance (IR) was determined by the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). MS was defined by the National Cholesterol Education Program Adult Treatment Panel III criteria modified by Cook. Results: The prevalence of MS was 15.8%. Abdominal obesity was present in all children. Frequency of elevated blood pressure, low HDL-cholesterol and elevated triglyceride concentrations were 62.6%, 13.4% and 11.0%, respectively. None of the children presented impaired fasting glucose, however hyperinsulinemia (7.3%) and IR (8.5%) were observed. The number of components of MS was higher in children with higher z-BMI (rho = 0.411; p < 0.001). MS was associated with higher leptin concentrations. No association was found with adiponectin or ghrelin levels. Leptin correlated positively with obesity, glucose metabolism, lipid profile, hepatic function and C-reactive protein, and negatively with HDL and Apolipoprotein A-I/B ratio. Conclusions: This study shows a significant prevalence of MS among obese schoolchildren. Abdominal obesity and elevated blood pressure were the most frequent components of this syndrome. Dyslipidemia, IR and high levels of leptin were also associated with MS in this young group.
2011
Autores
Monteiro Gaspar, MJM; Amaral, TF; Oliveira, BMPM; Borges, N;
Publicação
PSYCHOLOGY OF SPORT AND EXERCISE
Abstract
Objective: To evaluate, in pre-adolescents and adolescents, the frequency of body image dissatisfaction and distortion and to assess the association between these factors and physical activity and body mass index (BMI). Design: Cross-sectional study. Methods: 234 children (10-17 years) from a Porto high school were evaluated. Dissatisfaction with body image (FID) was assessed by Collins' child figure drawings for pre-adolescents and adolescents. FID was calculated as the discrepancy between the "ideal figure" and the "perceived figure". Body image distortion (BID) was calculated as the discrepancy between the "perceived figure" and the "real figure". The Baecke questionnaire was applied to determine the habitual physical activity index (HPAI) of each participant. Results: Girls were more dissatisfied than boys with their body image (68.1% vs 52.9%). A high proportion of students of both genders and age groups revealed BID (71.8%) with 51.3% underestimating their body image and 20.5% overestimating it. A negative association was found between the FID and BID (girls: r = -.259, p = .006: boys: r = -.414, p < .001). High levels of physical activity were associated with a protective effect on FID, OR = 0.38, 95% CI [0.16, 0.87] for 3rd vs 1st quartile of HPAI: OR = 0.29, 95% CI [0.12, 0.86], for 4th vs 1st quartile of HPAI, both adjusted for BMI and gender, but HPAI was not associated with BID. Conclusion: FID and BID are highly frequent and inversely associated. BID increases directly with BMI percentiles in both genders while physical activity has a protective effect on dissatisfaction of body image.
2011
Autores
Pedrosa, C; Oliveira, BMPM; Albuquerque, I; Simoes Pereira, C; Vaz de Almeida, M; Correia, F;
Publicação
EUROPEAN JOURNAL OF PEDIATRICS
Abstract
The aim of this study was to evaluate the effect of a lifestyle intervention programme (nutrition and exercise counselling) on metabolic syndrome (MS) components, adipokines (leptin, adiponectin) and ghrelin levels in overweight children. A total of 61 overweight children aged 7-9 years (>= 85th body mass index (BMI) percentile; 27 boys/34 girls) were randomly assigned and completed a 1-year individual (IT) or group-based treatment (GT). Anthropometric and biochemical parameters were assessed at baseline, at 6 months and at 1 year. Twenty-two normal weight children (< 85th BMI percentile; 7-9 years old; 13 boys/nine girls) were also evaluated at baseline. Insulin resistance (IR) was determined by the homeostasis model assessment of IR (HOMA-IR). Overweight children presented significantly higher blood pressure, triglycerides, apolipoprotein B, insulin, HOMA-IR, leptin, C-reactive protein and homocysteine levels, while apolipoprotein A-I was significantly lower. At baseline, MS was present in ten overweight children, of which only five maintained it at 1 year. Leptin and ghrelin levels were associated with IR and MS components. MS was predicted by apolipoprotein A-I, insulin and pre-puberty. The lifestyle intervention led to a significant improvement in standard deviation score of BMI, waist circumference/height ratio and lipid profile. Changes in insulin, HOMA-IR, leptin and adiponectin were not significant. Ghrelin behaved differently between IT and GT. The GT intervention seems to be more successful, with a decrease in BMI Z-score and an improvement of metabolic parameters. In conclusion, overweight children have multiple risk factors associated with MS. A lifestyle intervention programme seems to be an effective mean for reducing obesity and MS components and improving adipokines concentrations.
2011
Autores
Pedrosa, C; Oliveira, BMPM; Albuquerque, I; Simoes Pereira, C; Vaz de Almeida, MD; Correia, F;
Publicação
EUROPEAN JOURNAL OF NUTRITION
Abstract
Excess weight may be related to the development of adverse cardiometabolic risk factors in children. The aim of this study was to evaluate the effect of a lifestyle intervention program (nutrition and exercise counseling) on anthropometric parameters and metabolic syndrome (MS) components in Portuguese overweight/obese children. A total of 83 overweight/obese children aged 7-9 years were assigned to a 1-year individual or group-based treatment (GT); 61 children (z-score BMI (zBMI): 1.93 +/- A 0.28; 27 boys and 34 girls) completed the program. Anthropometric and biochemical parameters were assessed at baseline, at 6 months and at 1 year. The overweight/obese children, compared to normal-weight ones, presented significantly higher blood pressure, total-cholesterol, total-cholesterol/high density lipoprotein cholesterol (HDL) ratio, triglycerides, Apolipoprotein B and C-reactive protein levels, while HDL and Apolipoprotein A-I were significantly lower. At baseline, the prevalence of MS was 16.4% in overweight/obese and 0% in normal-weight children. The number of components of MS was significantly higher in children with higher zBMI. Lifestyle intervention led to a significant improvement in zBMI, waist circumference/height ratio, HDL, triglycerides, Apolipoprotein A-I, and Apolipoprotein B levels. The prevalence of MS decreased to 14.8%. The GT intervention seems to be more successful, with a significant decrease in zBMI and an increase in HDL and a lower drop-out rate. Overweight/obese children have multiple risk factors associated with the MS. Lifestyle intervention, both individual and group-based treatment, led to an improvement in the degree of overweight/obesity and in MS components.
2010
Autores
Carreira, H; Amaral, TF; Bras Silva, C; Oliveira, BMPM; Borges, N;
Publicação
ACTA MEDICA PORTUGUESA
Abstract
HAND GRIP STRENGTH IN A SAMPLE Of 11 to 14 Years Old Children Introduction: The determination of hand grip strength is an objective method of evaluation of upper members' integrity. It is also used as a general health indicator. Data about grip strength values in healthy children is useful in the research and diagnosis of diseases that interfere with grip force. The aim of this study was to determine average values of children hand grip strength by age and evaluate its relation with weight and height. Material and Methods: Hand grip strength was measured with the dynamometer Jamar Hydraulic Hand (R) in a convenience sample of 195 children of either gender, with ages between 11 and 14 years old. Results: Statistical significant differences were observed in hand grip strength between genders, being higher in boys. Moderate correlations were found between grip strength and age (R = 0.679, p < 0.001), height (R = 0.691, p < 0.001), and weight (R = 0.620, p < 0.001). Conclusion: The present study presents values of hand grip strength obtained from a sample of Portuguese children of 11 to 14 years old, which are directly associated with height and weight.
2010
Autores
Beca, A; Egipto, P; Carvalho, D; Correia, F; Oliveira, B; Rodrigues, A; Amarante, J; Medina, JL;
Publicação
ACTA MEDICA PORTUGUESA
Abstract
NITROGEN BALANCE ASSESSMENT IN BURN PATIENTS Introduction: The burn injury probably represents the largest stimulus for muscle protein catabolism. This state is characterized by an accelerated catabolism of the lean or skeletal mass that results in a clinical negative balance of nitrogen and muscle wasting. The determination of an appropriate value for protein intake is essential, since it is positively related to the nitrogen balance (NB) and accordingly several authors argue that a positive NB is the key parameter associated with nutritional improvement of a burn patient. Objectives: Evaluation of the degree of protein catabolism by assessment of the Nitrogen Balance; Defining of nutritional support (protein needs) to implement in patients with burned surface area (BSA) >= 10%. Methods: We prospectively evaluated the clinical files and scrutinized the clinical variables of interest. The NB was estimated according to three formulae. Each gram of nitrogen calculated by the NB was then converted into grams of protein, subtracted or added to protein intake (or administered enteric or parenterically) and divided by kg of reference Weight (kg Rweight), in an attempt to estimate the daily protein needs. Results: The cohort consisted of 10 patients, 6 females, with average age of 58(23) years old, a mean of BSA of 21.4(8.4)%, ranging from a minimum of 10.0% and maximum of 35.0%. On average, patients were 58 (23) years old. The average number of days of hospitalization in the burn unit was 64.8(36.5) days. We observed significant differences between the 3 methods used for calculating the NB (p = 0.004), on average the NB was positive. When the formula A was used the average value of NB was higher. Regarding the attempt to estimate the needs of g prot/kg Rweight/day most of the values did not exceed, on average, 2.6 g Prot/kg Rweight/day and no significant differences between patients with a BSA% of 10-20% and with BSA% > 20% were found. Conclusion: Despite being able to estimate the protein catabolism through these formulas and verifying that most values were above zero, wide individual fluctuations were visible over time. Based on the sample reference that recommends a value of 1.5-2 g Prot/kg Rweight/day, we can conclude it to be underestimated, when comparing with the mean value of 2.6 g Prot/kg Rweight/day we established.
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