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Publicações

Publicações por João Paulo Cunha

1997

SIGIF: A digital signal interchange format with application in neurophysiology

Autores
Cunha, MB; Cunha, JPS; Silva, TOE;

Publicação
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Abstract
In this paper, the authors describe a biomedical digital-signal interchange format. The format supports both raw and processed data, multiple segments, several signal structures and representations, and an open architecture. Its versatility and adaptability allows the software to take advantage of any particular features of the acquisition hardware. The format has been used and improved in routine work during a five-year period involving the cooperation between two hospitals and one engineering research center. In order to support the format, an object oriented C language library has been developed and is also shortly described.

2005

What does an epileptiform spike look like in MEG? Comparison between coincident EEG and MEG spikes

Autores
Fernandes, JM; da Silva, AM; Huiskamp, G; Velis, DN; Manshanden, I; de Munck, JC; da Silva, FL; Cunha, JPS;

Publicação
JOURNAL OF CLINICAL NEUROPHYSIOLOGY

Abstract
Recent investigations suggest that there are differences between the characteristics of EEG and MEG epileptiform spikes. The authors performed an objective characterization of the morphology of epileptiform spikes recorded simultaneously in both EEG and MEG to determine whether they present the same morphologic characteristics. Based on a stepwise approach, the authors performed a computer analysis of EEG and MEG of a set of coincident epileptiform transients selected by a senior clinical neurophysiologist in recordings of three patients with drug-resistant epilepsy. A computer-based algorithm was applied to extract parameters that could be used to describe quantitatively the morphology of the transients, followed by a statistical comparison over the extracted metrics of the EEG and MEG waveforms. EEG and MEG coincident events were statistically different with respect to several morphologic characteristics, such as duration, sharpness, and shape. The differences found appear to be a consequence of MEG signals not being influenced by volume propagation through the tissues with different conductivities that surround the brain, compared with EEG, and of the different orientation of the underlying dipolar sources. The results indicate that visual inspection of MEG spikes and automatic spike-detector algorithms should use criteria adapted to the specific characteristics of the MEG, and not simply those used on conventional EEG.

2011

Autonomic correlates of attachment insecurity in a sample of women with eating disorders

Autores
Dias, P; Soares, I; Klein, J; Cunha, JPS; Roisman, GI;

Publicação
ATTACHMENT & HUMAN DEVELOPMENT

Abstract
This study examined associations between attachment insecurity and autonomic response during the Adult Attachment Interview (AAI) in a sample of 47 women with eating disorders using a new system for the synchronous acquisition of behavioral and physiological data: the Bio Dual-channel and Representation of Attachment Multimedia System (BioDReAMS; Soares, Cunha, Zhan Jian Li, Pinho, Neves, 1998). Consistent with the emerging literature on the psychophysiology of adult attachment, insecurity was positively correlated with electrodermal reactivity during the AAI. Furthermore, relatively secure patients showed some evidence of parasympathetic withdrawal, which can be conceptualized as evidence of more effective emotion regulation. Results suggest that, even among women with diagnosed psychopathology, security is associated with moreproductive patterns of psychophysiological response to attachment-related challenges.

2002

Interictal spike EEG source analysis in hypothalamic hamartoma epilepsy

Autores
Leal, AJR; Passao, V; Calado, E; Vieira, JP; Cunha, JPS;

Publicação
CLINICAL NEUROPHYSIOLOGY

Abstract
Objective: The epilepsy associated with the hypothalamic hamartomas constitutes a syndrome with peculiar seizures, usually refractory to medical therapy, mild cognitive delay, behavioural problems and multifocal spike activity in the scalp electroencephalogram (EEG). The cortical origin of spikes has been widely assumed but not specifically demonstrated. Methods: We present results of a source analysis of interictal spikes from 4 patients (age 2-25 years) with epilepsy and hypothalamic hamartoma, using EEG scalp recordings (32 electrodes) and realistic boundary element models constructed from volumetric magnetic resonance imaging (MRIs). Multifocal spike activity was the most common finding, distributed mainly over the frontal and temporal lobes. A spike classification based on scalp topography was done and averaging within each class performed to improve the signal to noise ratio. Single moving dipole models were used, as well as the Rap-MUSIC algorithm. Results: All spikes with good signal to noise ratio were best explained by initial deep sources in the neighbourhood of the hamartoma, with late sources located in the cortex. Not a single patient could have his spike activity explained by a combination of cortical sources. Conclusions: Overall, the results demonstrate a consistent origin of spike activity in the subcortical region in the neighbourhood of the hamartoma, with late spread to cortical areas.

2012

Movement quantification in epileptic seizures: A feasibility study for a new 3D approach

Autores
Silva Cunha, JPS; Paula, LM; Bento, VF; Bilgin, C; Dias, E; Noachtar, S;

Publicação
MEDICAL ENGINEERING & PHYSICS

Abstract
Movement quantification of the human body is presently used for analyzing deficits resulting from Central Nervous System (CNS) pathologies or exploring the insights of the human motor system behaviour. Following our previous work on 2D movement quantification of epileptic seizures, we now present a feasibility study for a newly developed 3D technique. In order to validate this new 3D approach we made a comparison with the previous method. Both techniques were tested in two different datasets: a simple motor execution performed by a volunteer and a complex motor motion induced by a real epileptic seizure. The results obtained showed, as expected, the superior robustness and precision of the 3D approach but also confirmed the validity of the 2D method, given certain constraints. We conclude that the newly developed 3D system will highly improve our capacity of pursuing the clinical research on quantitative characterization of seizure semiology to support epilepsy diagnosis.

2012

iVital: A real time monitoring system for first response teams

Autores
Teles, DC; Colunas, MFM; Fernandes, JM; Oliveira, IC; Cunha, JPS;

Publicação
Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering

Abstract
Every day, thousands of first responders work to save the lives of others, sometimes without the adequate surveillance of health conditions. The VitalResponder is a project that aims at monitoring and control teams of first responders in emergency scenarios, using mobile technologies to capture and use real-time data to support real-time coordination. In this paper we present a system to capture, process, and display the vital signs of team members, which are made available to a first responders' team leader, for coordination and monitoring. The system addresses specific requirements of the field action, such as the mobility of actors, combining two of the most recent mobile technologies: the iPad (for the coordination view) and Android OS-based smartphones (for real-time sensor data acquisition). © 2012 ICST Institute for Computer Science, Social Informatics and Telecommunications Engineering.

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