2015
Autores
Micó, L; Sanches, JM; Cardoso, JS;
Publicação
Neurocomputing
Abstract
2023
Autores
Montenegro, H; Silva, W; Cardoso, JS;
Publicação
MEDICAL APPLICATIONS WITH DISENTANGLEMENTS, MAD 2022
Abstract
The lack of interpretability of Deep Learning models hinders their deployment in clinical contexts. Case-based explanations can be used to justify these models' decisions and improve their trustworthiness. However, providing medical cases as explanations may threaten the privacy of patients. We propose a generative adversarial network to disentangle identity and medical features from images. Using this network, we can alter the identity of an image to anonymize it while preserving relevant explanatory features. As a proof of concept, we apply the proposed model to biometric and medical datasets, demonstrating its capacity to anonymize medical images while preserving explanatory evidence and a reasonable level of intelligibility. Finally, we demonstrate that the model is inherently capable of generating counterfactual explanations.
2022
Autores
Huber, M; Boutros, F; Luu, AT; Raja, K; Ramachandra, R; Damer, N; Neto, PC; Goncalves, T; Sequeira, AF; Cardoso, JS; Tremoco, J; Lourenco, M; Serra, S; Cermeno, E; Ivanovska, M; Batagelj, B; Kronovsek, A; Peer, P; Struc, V;
Publicação
2022 IEEE INTERNATIONAL JOINT CONFERENCE ON BIOMETRICS (IJCB)
Abstract
This paper presents a summary of the Competition on Face Morphing Attack Detection Based on Privacy-aware Synthetic Training Data (SYN-MAD) held at the 2022 International Joint Conference on Biometrics (IJCB 2022). The competition attracted a total of 12 participating teams, both from academia and industry and present in 11 different countries. In the end, seven valid submissions were submitted by the participating teams and evaluated by the organizers. The competition was held to present and attract solutions that deal with detecting face morphing attacks while protecting people's privacy for ethical and legal reasons. To ensure this, the training data was limited to synthetic data provided by the organizers. The submitted solutions presented innovations that led to outperforming the considered baseline in many experimental settings. The evaluation benchmark is now available at: https://github.com/marcohuber/SYN-MAD-2022.
2021
Autores
de Sousa, IM; Oliveira, Md; Lisboa Filho, PN; Santos Cardoso, Jd;
Publicação
IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021, Houston, TX, USA, December 9-12, 2021
Abstract
Multiple Sclerosis (MS) is a chronic and inflammatory disorder that causes degeneration of axons in brain white matter and spinal cord. Magnetic Resonance Imaging (MRI) is extensively used to identify MS lesions and evaluate the progression of the disease, but the manual identification and quantification of lesions are time consuming and error-prone tasks. Thus, automated Deep Learning methods, in special Convolutional Neural Networks (CNNs), are becoming popular to segment medical images. It has been noticed that the performance of those methods tends to decrease when applied to MRI acquired under different protocols. The aim of this work is to statistically evaluate the possible influence of domain adaptation during the training process of CNNs models for segmenting MS lesions in MRI. The segmentation models were tested on MRIs (FLAIR and T1) of 20 patients diagnosed with Multiple Sclerosis. The set of segmented images of each different model was compared statistically, through the metrics Dice Similarity Coefficient (DSC), Predictive Positive Value (PPV) and Absolute Volume Difference (AVD). The results indicate that the domain adapted training can improve the performance of automatic segmentation methods, by CNNs, and have great potential to be used in medical clinics in the future. © 2021 IEEE.
2023
Autores
Albuquerque, T; Rosado, L; Cruz, RPM; Vasconcelos, MJM; Oliveira, T; Cardoso, JS;
Publicação
Intell. Syst. Appl.
Abstract
Microscopic techniques in low-to-middle income countries are constrained by the lack of adequate equipment and trained operators. Since light microscopy delivers crucial methods for the diagnosis and screening of numerous diseases, several efforts have been made by the scientific community to develop low-cost devices such as 3D-printed portable microscopes. Nevertheless, these devices present some drawbacks that directly affect image quality: the capture of the samples is done via mobile phones; more affordable lenses are usually used, leading to poorer physical properties and images with lower depth of field; misalignments in the microscopic set-up regarding optical, mechanical, and illumination components are frequent, causing image distortions such as chromatic aberrations. This work investigates several pre-processing methods to tackle the presented issues and proposed a new workflow for low-cost microscopy. Additionally, two new deep learning models based on Convolutional Neural Networks are also proposed (EDoF-CNN-Fast and EDoF-CNN-Pairwise) to generate Extended Depth of Field (EDoF) images, and compared against state-of-the-art approaches. The models were tested using two different datasets of cytology microscopic images: public Cervix93 and a new dataset that has been made publicly available containing images captured with µSmartScope. Experimental results demonstrate that the proposed workflow can achieve state-of-the-art performance when generating EDoF images from low-cost microscopes. © 2022 The Author(s)
2023
Autores
Castro, E; Pereira, JC; Cardoso, JS;
Publicação
MEDICAL IMAGE ANALYSIS
Abstract
Breast cancer is the most common and lethal form of cancer in women. Recent efforts have focused on developing accurate neural network-based computer-aided diagnosis systems for screening to help anticipate this disease. The ultimate goal is to reduce mortality and improve quality of life after treatment. Due to the difficulty in collecting and annotating data in this domain, data scarcity is - and will continue to be - a limiting factor. In this work, we present a unified view of different regularization methods that incorporate domain-known symmetries in the model. Three general strategies were followed: (i) data augmentation, (ii) invariance promotion in the loss function, and (iii) the use of equivariant architectures. Each of these strategies encodes different priors on the functions learned by the model and can be readily introduced in most settings. Empirically we show that the proposed symmetry-based regularization procedures improve generalization to unseen examples. This advantage is verified in different scenarios, datasets and model architectures. We hope that both the principle of symmetry-based regularization and the concrete methods presented can guide development towards more data-efficient methods for breast cancer screening as well as other medical imaging domains.
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